Journal ArticleDOI
Bioinspired Helical Microfibers from Microfluidics
Reads0
Chats0
TLDR
A coaxial capillary microfluidic system, with the functions of consecutive spinning and spiraling, is presented for scalable generation of helical microfibers with structures such as the novel Janus, triplex, core–shell, and even double‐helix structures.Abstract:
Helical objects are among the most important and landmark structures in nature, and represent an emerging group of materials with unique spiral geometry; because of their enriched physical and chemical properties, they can have multiple functionalities. However, the fabrication of such complex helical materials at the micro- or nanoscale level remains a challenge. Here, a coaxial capillary microfluidic system, with the functions of consecutive spinning and spiraling, is presented for scalable generation of helical microfibers. The generation processes can be precisely tuned by adjusting the flow rates, and thus the length, diameter, and pitch of the helical microfibers are highly controllable. Varying the injection capillary design of the microfluidics enables the generation of helical microfibers with structures such as the novel Janus, triplex, core-shell, and even double-helix structures. The potential use of these helical microfibers is also explored for magnetically and thermodynamically triggered microsprings, as well as for a force indicator for contraction of cardiomyocytes. These indicate that such helical microfibers are highly versatile for different applications.read more
Citations
More filters
Journal ArticleDOI
Degradable conductive injectable hydrogels as novel antibacterial, anti-oxidant wound dressings for wound healing
TL;DR: In vivo experiments indicated that hydrogel with AT addition (OHA-AT/CEC hydrogels) significantly accelerated wound healing rate with higher granulation tissue thickness, collagen disposition and more angiogenesis in a full-thickness skin defect model.
Journal ArticleDOI
Bioinspired living structural color hydrogels
TL;DR: By integrating the biohybrid structural color hydrogels into microfluidics, this paper developed a “heart-on-a-chip” platform featuring microphysiological visuality for biological research and drug screening and may be widely used in the design of a variety of intelligent actuators and soft robotic devices.
Journal ArticleDOI
Application Challenges in Fiber and Textile Electronics.
Lie Wang,Xuemei Fu,Jiqing He,Xiang Shi,Taiqiang Chen,Peining Chen,Bingjie Wang,Huisheng Peng +7 more
TL;DR: The application challenges faced by fiber and textile electronics from single fiber-shaped devices to continuously scalable fabrication, to encapsulation and testing, to application mode exploration, and to future directions required to boost their commercialization are highlighted.
Journal ArticleDOI
Bioinspired Multifunctional Hybrid Hydrogel Promotes Wound Healing
TL;DR: It is demonstrated that acute tissue injuries such as vessel bleeding and liver bleeding can be repaired immediately because of the outstanding adhesion and hemostasis features of the multifunctional hybrid hydrogel.
Journal ArticleDOI
Biomimetic enzyme cascade reaction system in microfluidic electrospray microcapsules.
TL;DR: A novel multienzyme system based on hollow hydrogel microcapsules with flexible enzymatic inverse opal particles that could act as a cascade biocatalyst and reduce alcohol levels in media, providing an alternative antidote and prophylactic for alcohol intoxication.
References
More filters
Journal ArticleDOI
Directional water collection on wetted spider silk
TL;DR: Artificial fibres are designed that mimic the structural features of silk and exhibit its directional water-collecting ability by tapping into both driving forces.
Journal ArticleDOI
Continuous directional water transport on the peristome surface of Nepenthes alata
Huawei Chen,Pengfei Zhang,Liwen Zhang,Hongliang Liu,Y. Jiang,Deyuan Zhang,Zhiwu Han,Lei Jiang,Lei Jiang +8 more
TL;DR: It is found that continuous, directional water transport occurs on the surface of the ‘peristome’—the rim of the pitcher—because of its multiscale structure, which optimizes and enhances capillary rise in the transport direction, and prevents backflow by pinning in place any water front that is moving in the reverse direction.
Journal ArticleDOI
Assembly of micro/nanomaterials into complex, three-dimensional architectures by compressive buckling
Sheng Xu,Zheng Yan,Kyung In Jang,Wen Huang,Fu Haoran,Fu Haoran,Jeonghyun Kim,Jeonghyun Kim,Zijun Wei,Matthew T. Flavin,Joselle M. McCracken,Renhan Wang,Adina Badea,Yuhao Liu,Dongqing Xiao,Guoyan Zhou,Guoyan Zhou,Jung Woo Lee,Jung Woo Lee,Ha Uk Chung,Huanyu Cheng,Huanyu Cheng,Wen Ren,Anthony Banks,Xiuling Li,Ungyu Paik,Ralph G. Nuzzo,Yonggang Huang,Yihui Zhang,Yihui Zhang,John A. Rogers +30 more
TL;DR: An ingenious design strategy for the microfabrication of complex geometric 3D mesostructures that derive from the out-of-plane buckling of an originally planar structural layout is developed.
Journal ArticleDOI
Metre-long cell-laden microfibres exhibit tissue morphologies and functions
Hiroaki Onoe,Teru Okitsu,Akane Itou,Midori Kato-Negishi,Riho Gojo,Daisuke Kiriya,Koji Sato,Shigenori Miura,Shintaroh Iwanaga,Kaori Kuribayashi-Shigetomi,Yukiko T. Matsunaga,Yuto Shimoyama,Shoji Takeuchi +12 more
TL;DR: Fibres encapsulating primary pancreatic islet cells and transplanted through a microcatheter into the subrenal capsular space of diabetic mice normalized blood glucose concentrations for about two weeks and may find use as templates for the reconstruction of fibre-shaped functional tissues that mimic muscle fibres, blood vessels or nerve networks in vivo.
Journal ArticleDOI
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
Gang Wang,Megan L. McCain,Luhan Yang,Aibin He,Francesco S. Pasqualini,Ashutosh Agarwal,Hongyan Yuan,Dawei Jiang,Donghui Zhang,Lior Zangi,Judith Geva,Amy E. Roberts,Qing Ma,Jian-Ping Ding,Jinghai Chen,Da-Zhi Wang,Kai Li,Jiwu Wang,Ronald J.A. Wanders,Wim Kulik,Frédéric M. Vaz,Michael A. Laflamme,Charles E. Murry,Kenneth R. Chien,Richard I. Kelley,George M. Church,Kevin Kit Parker,William T. Pu +27 more
TL;DR: This study combined patient-derived and genetically engineered induced pluripotent stem cells (iPSCs) with tissue engineering to elucidate the pathophysiology underlying the cardiomyopathy of Barth syndrome, a mitochondrial disorder caused by mutation of the gene encoding tafazzin (TAZ).