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Journal ArticleDOI

Biological effects of racemic and resolved 13β-ethyl-4-gonen-3-ones

Richard A. Edgren, +4 more
- 01 Dec 1963 - 
- Vol. 2, Iss: 6, pp 731-737
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TLDR
In this article, the effects of (±)-13β, 17α-diethyl-17β-hydroxygon-4-en-3-one were compared with resolved samples of the component enantiomers.
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This article is published in Steroids.The article was published on 1963-12-01. It has received 36 citations till now.

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Citations
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Journal ArticleDOI

On the mechanisms of action of short-term levonorgestrel administration in emergency contraception

TL;DR: The effects of short-term administration of levonorgestrel (LNG) at different stages of the ovarian cycle on the pituitary-ovarian axis, corpus luteum function, and endometrium were investigated as mentioned in this paper.

Original research article On the mechanisms of action of short-term levonorgestrel administration in emergency contraception

TL;DR: It is suggested that interference of LNG with the mechanisms initiating the LH preovulatory surge depends on the stage of follicle development, and anovulation results from disrupting the normal development and/or the hormonal activity of the growing follicle only when LNG is givenPreovulatory.
Journal ArticleDOI

Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids

TL;DR: There is limited information on the metabolism of levonorgestrel, norethindrone and structurally related contraceptive steroids, and it appears that neither desogestrel nor gestodene are transformed to the parent compound.
Journal ArticleDOI

Sex hormone binding globulin capacity as an index of oestrogenicity or androgenicity in women on oral contraceptive steroids

TL;DR: Women with a high pre‐treatment SHBG level might be more suited to combination OC with d‐norgestrel or the 19‐norprogestagen‘mini’pills, while combined OC preparations causing some elevation of SHBG might be preferable.
Journal ArticleDOI

The influence of hormonal contraceptives on sex hormone binding globulin (SHBG) capacity.

TL;DR: It appeared that the SHBG response to OCs is different from that of transcortin-binding capacity, and the combination of ethinyl estradiol with megestrol acetate gave results comparable with those attained during pregnancy.
References
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About steroids; the synthesis of natural oestrone; total syntheses in the Oestron series III.

TL;DR: Ausgehend von einem sterisch einheitlichen Ketoester der Phenanthrenreihe (Ia), wird die Synthese zweier racemischer Oestrone XI a and XIb beschrieben.
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