Biomaterials & scaffolds for tissue engineering
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TLDR
The functional requirements, and types, of materials used in developing state of the art of scaffolds for tissue engineering applications are described and where future research and direction is required are described.About:
This article is published in Materials Today.The article was published on 2011-03-01 and is currently open access. It has received 2648 citations till now. The article focuses on the topics: Tissue engineering.read more
Citations
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Hyaluronic acid based scaffolds for tissue engineering--a review.
TL;DR: This review focuses on hyaluronic acid (HA) tissue scaffolding materials and the latest technologies behind scaffold processing are assessed and the applications of HA based scaffolds are discussed.
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Scaffolds for Bone Tissue Engineering: State of the art and new perspectives.
Livia Roseti,V. Parisi,Mauro Petretta,Carola Cavallo,Giovanna Desando,Isabella Bartolotti,Brunella Grigolo +6 more
TL;DR: It is highlighted that, despite its encouraging results, the clinical approach of Bone Tissue Engineering has not taken place on a large scale yet, due to the need of more in depth studies, its high manufacturing costs and the difficulty to obtain regulatory approval.
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Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects
TL;DR: In this paper, the authors highlight contemporary tendencies in application of non-degradable scaffolds and stem cells in regenerative medicine with a particular focus on the pore sizes significantly affecting final recover of diseased organs.
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Bone biomaterials and interactions with stem cells.
TL;DR: A comprehensive review of the state of the art of bone biomaterials and their interactions with stem cells is presented and the promising seed stem cells for bone repair are summarized, and their interaction mechanisms are discussed in detail.
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Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration.
TL;DR: This review highlights the current research in bone biofabrication, the necessary factors for success, in addition to the current limitations affecting biofabricsation, some of which are a consequence of the limitations of the additive manufacturing technology itself.
References
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Matrix elasticity directs stem cell lineage specification.
TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
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Scaffolds in tissue engineering bone and cartilage.
TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
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Growth Factors, Matrices, and Forces Combine and Control Stem Cells
TL;DR: Multifaceted technologies are increasingly required to produce and interrogate cells ex vivo, to build predictive models, and, ultimately, to enhance stem cell integration in vivo for therapeutic benefit.
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Tissue-engineered autologous bladders for patients needing cystoplasty
TL;DR: Engineered bladder tissues, created with autologous cells seeded on collagen-polyglycolic acid scaffolds, and wrapped in omentum after implantation, can be used in patients who need cystoplasty.
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The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering
TL;DR: The results show that cell number was highest in scaffolds with the largest pore size, which was deemed optimal for bone tissue engineering, and an added advantage of the larger pores is a reduction in cell aggregations that develop along the edges of the scaffolds.