Biosynthesis of nanoparticles and silver nanoparticles
TL;DR: In this paper, a review of the green synthesis of silver nanoparticles is presented, which showed more cost-effective and environmental friendly application as well as easier for large production, with relation to the properties of the nanoparticles as antimicrobial, can be served as an alternative antiseptic agent in various fields.
Abstract: In this century, the development of nanotechnology is projected to be the establishment of a technological evolutionary of this modern era. Recently, nanotechnology is one of the most active subjects of substantial research in modern material sciences and hence metal nanoparticles have a great scientific interest because of their unique optoelectronic and physicochemical properties with applications in diverse areas such as electronics, catalysis, drug delivery, or sensing. Nanotechnology provides an understanding on fundamental properties of objects at the atomic, molecular, and supramolecular levels. Besides, nanotechnology also leads an alternative technological pathway for the exploration and revolution of biological entities, whereas biology provides role models and biosynthetic constituents to nanotechnology. The findings of this review are important to provide an alternative for the green synthesis of silver nanoparticles. It showed more cost-effective and environmental friendly application as well as easier for large production, with relation to the properties of silver nanoparticles as antimicrobial, can be served well as an alternative antiseptic agent in various fields. Typically, silver nanoparticles are smaller than 100 nm and consist of about 20–15,000 silver atoms. Due to the attractive physical and chemical properties of silver at the nanoscale, the development of silver nanoparticles is expanding in recent years and is nowadays significant for consumer and medical products.
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TL;DR: The methods of making nanoparticles using plant extracts are reviewed, methods of particle characterization are reviewed and potential applications of the particles in medicine are discussed.
1,706 citations
TL;DR: A state-of-the-art review on the synthesis of AgNPs, and their applications in antimicrobial textile fabrics, food packaging films, and wound dressings is provided.
Abstract: Silver nanoparticles (AgNPs) can be synthesized from a variety of techniques including physical, chemical and biological routes. They have been widely used as nanomaterials for manufacturing cosmetic and healthcare products, antimicrobial textiles, wound dressings, antitumor drug carriers, etc. due to their excellent antimicrobial properties. Accordingly, AgNPs have gained access into our daily life, and the inevitable human exposure to these nanoparticles has raised concerns about their potential hazards to the environment, health, and safety in recent years. From in vitro cell cultivation tests, AgNPs have been reported to be toxic to several human cell lines including human bronchial epithelial cells, human umbilical vein endothelial cells, red blood cells, human peripheral blood mononuclear cells, immortal human keratinocytes, liver cells, etc. AgNPs induce a dose-, size- and time-dependent cytotoxicity, particularly for those with sizes ≤10 nm. Furthermore, AgNPs can cross the brain blood barrier of mice through the circulation system on the basis of in vivo animal tests. AgNPs tend to accumulate in mice organs such as liver, spleen, kidney and brain following intravenous, intraperitoneal, and intratracheal routes of administration. In this respect, AgNPs are considered a double-edged sword that can eliminate microorganisms but induce cytotoxicity in mammalian cells. This article provides a state-of-the-art review on the synthesis of AgNPs, and their applications in antimicrobial textile fabrics, food packaging films, and wound dressings. Particular attention is paid to the bactericidal activity and cytotoxic effect in mammalian cells.
510 citations
TL;DR: The present review highlights the antimicrobial effects of various nanomaterials and their potential advantages, drawbacks, or side effects and may be useful in the discovery of broad-spectrum antimicrobial drugs for use against multi-drug-resistant microbial pathogens in the near future.
Abstract: Antimicrobial substances may be synthetic, semisynthetic, or of natural origin (i.e., from plants and animals). Antimicrobials are considered “miracle drugs” and can determine if an infected patient/animal recovers or dies. However, the misuse of antimicrobials has led to the development of multi-drug-resistant bacteria, which is one of the greatest challenges for healthcare practitioners and is a significant global threat. The major concern with the development of antimicrobial resistance is the spread of resistant organisms. The replacement of conventional antimicrobials by new technology to counteract antimicrobial resistance is ongoing. Nanotechnology-driven innovations provide hope for patients and practitioners in overcoming the problem of drug resistance. Nanomaterials have tremendous potential in both the medical and veterinary fields. Several nanostructures comprising metallic particles have been developed to counteract microbial pathogens. The effectiveness of nanoparticles (NPs) depends on the interaction between the microorganism and the NPs. The development of effective nanomaterials requires in-depth knowledge of the physicochemical properties of NPs and the biological aspects of microorganisms. However, the risks associated with using NPs in healthcare need to be addressed. The present review highlights the antimicrobial effects of various nanomaterials and their potential advantages, drawbacks, or side effects. In addition, this comprehensive information may be useful in the discovery of broad-spectrum antimicrobial drugs for use against multi-drug-resistant microbial pathogens in the near future.
365 citations
Cites background from "Biosynthesis of nanoparticles and s..."
...AgNPs exhibit superior antimicrobial properties mediated by the synthesis of reactive oxygen species (ROS) including hydrogen peroxide [43,45,55]....
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...AgNPs are a good source of antimicrobial agents and possess antioxidant, anti-inflammatory, anticancer, and antiangiogenic activities [27,31,44,55]....
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TL;DR: It is expected that metal-supported nanomaterials play an outstanding role not only in medical but also in other important areas such as antibacterial, antifungal, anticancer, and so on.
Abstract: Nanoparticles (nanoparticles) have received much attention in biological application because of their unique physicochemical properties. The metal- and metal oxide-supported nanomaterials have shown significant therapeutic effect in medical science. The mechanisms related to the interaction of nanoparticles with animal and plant cells can be used to establish its significant role and to improve their activity in health and medical applications. Various attempts have been made to discuss the antibiotic resistance and antimicrobial activity of metal-supported nanoparticles. Despite all these developments, there is still a need to investigate their performance to overcome modern challenges. In this regard, the present review examines the role of various types of metal-supported nanomaterials in different areas such as antibacterial, antifungal, anticancer, and so on. Based on the significant ongoing research and applications, it is expected that metal-supported nanomaterials play an outstanding role not only in medical but also in other important areas.
319 citations
TL;DR: The microorganism/plant extract and the reaction parameters used in synthesis of the AgNPs, which hold prominent impact on their size, shape, and application are described.
Abstract: Nanoparticle biosynthetic discipline is still under development and is known to have a big impact on numerous manufactures for a long time. Nowadays, biosynthesis of silver nanoparticles (AgNPs) had gained so much attention in developed countries due to development demand of environmental friendly technology for material synthesis. The use of green chemistry is environmental friendly, non-toxic, and cheap. This review focused on the recent scientific publications in the green synthesis field of AgNPs and its applications. A number of microorganisms including bacteria, fungi, yeasts, algae, and plants either intra- or extracellular have been found to be capable of synthesizing AgNPs. All scientific reports reflect the unique properties AgNPs possess that find myriad applications such as antibacterial, antifungal, antivirus, and anticancer drugs, larvicidal excellent catalytic natural action towards degradation of dyes, very good antioxidants, treatment of diabetes-related complications, and wound healing activities. The recent strategy for improving the efficacy of antibiotics is to combine them with AgNPs in order to control the microbial infections as confirmed by the damage action of AgNPs on microbial deoxyribonucleic acid. This review describes also the microorganism/plant extract and the reaction parameters used in synthesis of the AgNPs, which hold prominent impact on their size, shape, and application. Recently published information on AgNP synthesis and its applications are summarized in this review.
255 citations
References
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TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.
Abstract: Nanotechnology is expected to open new avenues to fight and prevent disease using atomic scale tailoring of materials. Among the most promising nanomaterials with antibacterial properties are metallic nanoparticles, which exhibit increased chemical activity due to their large surface to volume ratios and crystallographic surface structure. The study of bactericidal nanomaterials is particularly timely considering the recent increase of new resistant strains of bacteria to the most potent antibiotics. This has promoted research in the well known activity of silver ions and silver-based compounds, including silver nanoparticles. The present work studies the effect of silver nanoparticles in the range of 1-100 nm on Gram-negative bacteria using high angle annular dark field (HAADF) scanning transmission electron microscopy (STEM). Our results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.
5,609 citations
TL;DR: This is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and the results demonstrate thatsilver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
Abstract: In this work we investigated the antibacterial properties of differently shaped silver nanoparticles against the gram-negative bacterium Escherichia coli, both in liquid systems and on agar plates. Energy-filtering transmission electron microscopy images revealed considerable changes in the cell membranes upon treatment, resulting in cell death. Truncated triangular silver nanoplates with a {111} lattice plane as the basal plane displayed the strongest biocidal action, compared with spherical and rod-shaped nanoparticles and with Ag+ (in the form of AgNO3). It is proposed that nanoscale size and the presence of a {111} plane combine to promote this biocidal property. To our knowledge, this is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and our results demonstrate that silver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
3,697 citations
TL;DR: This review presents an overview of silver nanoparticles (Ag NPs) preparation by green synthesis approaches that have advantages over conventional methods involving chemical agents associated with environmental toxicity.
3,290 citations
"Biosynthesis of nanoparticles and s..." refers background in this paper
...For examples, a silver salt, Ag2SO4, and polyoxometalates (NH4)10[Mo)4(Mo)2O14 (O3PCH2PO3)2(HO3PCH2PO3)2]-15 H2O and H7[βP(Mo)4(Mo)8O40] reacted to fabricate spherical and quasi-monodispersed silver nanoparticles with a diameter of about 38 nm after several minutes (Sharma et al. 2009)....
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TL;DR: Most of the plants used in metal nanoparticle synthesis are shown in this article, and the advantages of using plant and plant-derived materials for biosynthesis of metal nanoparticles have interested researchers to investigate mechanisms of metal ions uptake and bioreduction by plants, and to understand the possible mechanism of nanoparticle formation in plants.
2,424 citations
"Biosynthesis of nanoparticles and s..." refers background in this paper
...In recent years, biosynthesis of metal nanoparticles, especially silver and gold nanoparticles, using plant extracts as nano-factories becomes an important subject of researches in the field of bio-nanotechnology (Iravani 2011)....
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...The biobased protocols for synthesis of nano-metals are both environmentally and economically green as they are based on green chemistry principles and are simple, relatively inexpensive, and easily scaled up for larger scale production (Mohanpuria et al. 2008; Iravani 2011; Prabhu and Poulose 2012)....
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...2008; Iravani 2011; Prabhu and Poulose 2012)....
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TL;DR: The antimicrobial mechanisms of several nanoparticles are reviewed, their merits, limitations and applicability for water disinfection and biofouling control are discussed, and research needs to utilize novel nanomaterials for water treatment applications are highlighted.
2,108 citations
"Biosynthesis of nanoparticles and s..." refers background in this paper
...Instead, there are three possible antibacterial mechanisms of silver nanoparticles that have been proposed by Li and coworkers (Li et al. 2008):...
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