Journal ArticleDOI
Blast-related traumatic brain injury
Jeffrey V. Rosenfeld,Jeffrey V. Rosenfeld,Alexander C. McFarlane,Peter Bragge,Rocco A. Armonda,Rocco A. Armonda,Jamie B Grimes,Geoffrey S.F. Ling,Geoffrey S.F. Ling +8 more
Reads0
Chats0
TLDR
Persistent impairment after blast-related Mild TBI might be largely attributable to psychological factors, although a causative link between repeated mild TBIs caused by blasts and chronic traumatic encephalopathy has not been established.Citations
More filters
Journal ArticleDOI
Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurological Outcomes
TL;DR: Many of the pathophysiological mechanisms felt to be active in the acute and long-term consequences of TBI include excitotoxicity, apoptosis, inflammatory events, seizures, demyelination, white matter pathology, as well as decreased neurogenesis.
Journal ArticleDOI
Characterisation of interface astroglial scarring in the human brain after blast exposure: a post-mortem case series.
Sharon B. Shively,Sharon B. Shively,Iren Horkayne-Szakaly,Robert V. Jones,James P. Kelly,Regina C. Armstrong,Daniel P. Perl +6 more
TL;DR: The blast exposure cases showed a distinct and previously undescribed pattern of interface astroglial scarring at boundaries between brain parenchyma and fluids, and at junctions between grey and white matter, which may indicate specific areas of damage from blast exposure consistent with the general principles of blast biophysics.
Book ChapterDOI
Classification of traumatic brain injury: past, present, and future.
TL;DR: The characteristics of an ideal classification system and the unique challenges inherent to achieving such a system for TBI are discussed, as are the strengths and limitations of these approaches.
Journal ArticleDOI
Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves
Ashok K. Shetty,Ashok K. Shetty,Vikas Mishra,Vikas Mishra,Maheedhar Kodali,Maheedhar Kodali,Bharathi Hattiangady,Bharathi Hattiangady +7 more
TL;DR: This review discusses studies that examined alterations in the brain milieu causing dysfunction or disruption of the blood-brain barrier and neuroinflammation following exposure to different intensities of BSWs.
Journal ArticleDOI
Current Concepts in Penetrating and Blast Injury to the Central Nervous System
TL;DR: Urgent resuscitation, correction of coagulopathy and early surgery with wide cranial decompression may improve the outcome in selected patients with severe craniocerebral GSW.
References
More filters
Journal ArticleDOI
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
Amit Etkin,Tor D. Wager +1 more
TL;DR: A meta-analysis of functional magnetic resonance imaging and positron emission tomography studies of posttraumatic stress disorder, social anxiety disorder, specific phobia, and fear conditioning in healthy individuals provided neuroimaging evidence for common brain mechanisms in anxiety disorders and normal fear.
Journal ArticleDOI
Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq
Charles W. Hoge,Dennis McGurk,Jeffrey L. Thomas,Anthony L. Cox,Charles C. Engel,Carl A. Castro +5 more
TL;DR: Mildtraumatic brain injury occurring among soldiers deployed in Iraq is strongly associated with PTSD and physical health problems 3 to 4 months after the soldiers return home, and after adjustment for PTSD and depression, mild traumatic brain injury was no longer significantly associated with these physical health outcomes or symptoms, except for headache.
Journal ArticleDOI
Traumatic brain injury.
TL;DR: Quantification of cerebral perfusion by monitoring of intracranial pressure and treatment of cerebral hypoperfusion decrease secondary injury and an organised trauma system that allows rapid resuscitation and transport directly to an experienced trauma centre significantly lowers mortality and morbidity.
Journal ArticleDOI
Consensus statement on Concussion in Sport - The 4th International Conference on Concussion in Sport held in Zurich, November 2012
Paul McCrory,Willem H. Meeuwisse,Mark Aubry,Bob Cantu,Jiří Dvořák,Ruben J. Echemendia,Lars Engebretsen,Lars Engebretsen,Karen M. Johnston,Jeff Kutcher,Martin Raftery,Allen K. Sills,Brian W. Benson,Gavin A Davis,Richard G. Ellenbogen,Kevin M. Guskiewicz,Stanley A. Herring,Grant L. Iverson,Barry D. Jordan,Barry D. Jordan,James Kissick,Michael McCrea,Andrew S. McIntosh,Andrew S. McIntosh,David Maddocks,Michael Makdissi,Michael Makdissi,Laura Purcell,Margot Putukian,Margot Putukian,Kathryn J Schneider,Charles H. Tator,Michael Turner +32 more
TL;DR: The 4th International Conference on Concussion in Sport held in Zurich, November 2012 was attended by Paul McCrory, Willem H Meeuwisse, Mark Aubry, Jiří Dvořák, Ruben J Echemendia, Lars Engebretsen, Karen Johnston, Jeffrey S Kutcher, Martin Raftery, Allen Sills and Kathryn Schneider.
Journal ArticleDOI
Consensus statement on concussion in sport
Paul McCrory,Willem H. Meeuwisse,Mark Aubry,Bob Cantu,Jiří Dvořák,Ruben J. Echemendia,Lars Engebretsen,Karen M. Johnston,Jeffrey S. Kutcher,Martin Raftery,Allen Sills,Brian W. Benson,Gavin A Davis,Richard G. Ellenbogen,Kevin M. Guskiewicz,Stanley A. Herring,Grant L. Iverson,Barry D. Jordan,James Kissick,Michael McCrea,Andrew S. McIntosh,David Maddocks,Michael Makdissi,Laura Purcell,Margot Putukian,Kathryn J Schneider,Charles H. Tator,Michael Turner +27 more
TL;DR: This paper is a revision and update of the recommendations developed following the 1st (Vienna 2001), 2nd (Prague 2004) and 3rd (Zurich 2008) International Consensus Conferences on Concussions in Sport and is based on the deliberations at the 4th International Conference on Concussion in Sport held in Zurich, November 2012.
Related Papers (5)
Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.
Lee E. Goldstein,Andrew M. Fisher,Chad A. Tagge,Xiao-Lei Zhang,Libor Velíšek,John A. Sullivan,Chirag Upreti,Jonathan M. Kracht,Maria Ericsson,Mark W. Wojnarowicz,Cezar Goletiani,Giorgi Maglakelidze,Noel Casey,Juliet A. Moncaster,Olga Minaeva,Robert D. Moir,Christopher J. Nowinski,Robert S. Stern,Robert C. Cantu,Robert C. Cantu,James Geiling,Jan Krzysztof Blusztajn,Benjamin Wolozin,Tsuneya Ikezu,Thor D. Stein,Thor D. Stein,Andrew E. Budson,Andrew E. Budson,Neil W. Kowall,Neil W. Kowall,David Chargin,Andre Sharon,Sudad Saman,Garth F. Hall,William C. Moss,Robin O. Cleveland,Rudolph E. Tanzi,Patric K. Stanton,Ann C. McKee,Ann C. McKee +39 more