Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology.
Phillippe Gabriel Steg,Kurt Huber,Felicita Andreotti,Harald Arnesen,Dan Atar,Lina Badimon,J.-P Bassand,R. De Caterina,J. A. Eikelboom,Dietrich C. Gulba,Martial Hamon,Gérard Helft,Keith A.A. Fox,Steen Dalby Kristensen,Sunil V. Rao,F. W. A. Verheugt,Petr Widimsky,Uwe Zeymer,Jean-Philippe Collet +18 more
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TLDR
Current knowledge regarding the epidemiology of bleeding in ACS and percutaneous coronary intervention is summarized, including measurement and definitions of bleeding, with emphasis on the recent consensus Bleeding Academic Research Consortium (BARC) definitions.Abstract:
Bleeding has recently emerged as an important outcome in the management of acute coronary syndromes (ACS), which is relatively frequent compared with ischaemic outcomes and has important implications in terms of prognosis, outcomes, and costs. In particular, there is evidence that patients experiencing major bleeding in the acute phase are at higher risk for death in the following months, although the causal nature of this relation is still debated. This position paper aims to summarize current knowledge regarding the epidemiology of bleeding in ACS and percutaneous coronary intervention, including measurement and definitions of bleeding, with emphasis on the recent consensus Bleeding Academic Research Consortium (BARC) definitions. It also provides an European perspective on management strategies to minimize the rate, extent, and consequences of bleeding. Finally, the research implications of bleeding (measuring and reporting bleeding in trials, the importance of bleeding as an outcome measure, and bleeding as a subject for future research) are also discussed.read more
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2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)
Marco Roffi,Carlo Patrono,Jean-Philippe Collet,Christian Mueller,Marco Valgimigli,Felicita Andreotti,Jeroen J. Bax,Michael A. Borger,Carlos Brotons,Derek P. Chew,Baris Gencer,Gerd Hasenfuss,Keld Kjeldsen,Patrizio Lancellotti,Ulf Landmesser,Julinda Mehilli,Debabrata Mukherjee,Robert F. Storey,Stephan Windecker +18 more
TL;DR: The current guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation are based on the findings of the ESC Task Force on 12 March 2015.
Journal ArticleDOI
2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).
Stephan Windecker,Philippe Kolh,Fernando Alfonso,Jean-Philippe Collet,Jochen Cremer,Volkmar Falk,Gerasimos Filippatos,Christian W. Hamm,Stuart J. Head,Peter Jüni,A. Pieter Kappetein,Adnan Kastrati,Juhani Knuuti,Ulf Landmesser,Günther Laufer,Franz-Josef Neumann,Dimitrios J. Richter,Patrick Schauerte,Miguel Sousa Uva,Giulio G. Stefanini,David P. Taggart,Lucia Torracca,Marco Valgimigli,William Wijns,Adam Witkowski +24 more
TL;DR: Neumann et al. as discussed by the authors proposed a task force to evaluate the EACTS Review Co-ordinator's work on gender equality in the context of women's reproductive health.
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2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
Ezra A. Amsterdam,Nanette K. Wenger,Ralph G. Brindis,Donald E. Casey,Theodore G. Ganiats,David R. Holmes,Allan S. Jaffe,Hani Jneid,Rosemary F. Kelly,Michael C. Kontos,Glenn N. Levine,Philip R. Liebson,Debabrata Mukherjee,Eric D. Peterson,Marc S. Sabatine,Richard W. Smalling,Susan J. Zieman +16 more
TL;DR: In this article, Anderson et al. discuss the FAHA chair election process and discuss the state of the art in the field of cancer research. But they do not discuss the role of women in this process.
Journal ArticleDOI
2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS).
Marco Valgimigli,Héctor Bueno,Robert A. Byrne,Jean-Philippe Collet,Francesco Costa,Anders Jeppsson,Peter Jüni,Adnan Kastrati,Philippe Kolh,Laura Mauri,Gilles Montalescot,Franz-Josef Neumann,Mate Petricevic,Marco Roffi,Philippe Gabriel Steg,Stephan Windecker,José Luis Zamorano,Glenn N. Levine,Lina Badimon,Pascal Vranckx,Stefan Agewall,Felicita Andreotti,Elliott M. Antman,Emanuele Barbato,Jean-Pierre Bassand,Raffaele Bugiardini,Mustafa Cikirikcioglu,Thomas Cuisset,Michele De Bonis,Victora Delgado,Donna Fitzsimons,Oliver Gaemperli,Nazzareno Galiè,Martine Gilard,Christian W. Hamm,Borja Ibanez,Bernard Iung,Stefan James,Juhani Knuuti,Ulf Landmesser,Christophe Leclercq,Maddalena Lettino,Gregory Y.H. Lip,Massimo F Piepoli,Luc Pierard,Markus Schwerzmann,Udo Sechtem,Iain A. Simpson,Miguel Sousa Uva,Eugenio Stabile,Robert F. Storey,Michal Tendera,Frans Van de Werf,Freek W.A. Verheugt,Victor Aboyans,Antonio Coca,I M Coman,Veronica Dean,Victoria Delgado,Gerhard Hindricks,Hugo A. Katus,Patrizio Lancellotti,Theresa McDonagh,Piotr Ponikowski,Dimitrios J. Richter,Evgeny Shlyakhto,Franz Xaver Roithinger,Farid Aliyev,Valeriy Stelmashok,Walter Desmet,Arman Postadzhiyan,Georgios P Georghiou,Zuzana Motovska,Erik Lerkevang Grove,Toomas Marandi,Tuomas Kiviniemi,Sasko Kedev,Steffen Massberg,Dimitrios Alexopoulos,Róbert Gábor Kiss,Ingibjorg Jona Gudmundsdottir,Eugene P. McFadden,Eli I. Lev,Leonardo De Luca,Akhmetzhan Sugraliyev,Edmond Haliti,Erkin M. Mirrakhimov,Gustavs Latkovskis,Birute Petrauskiene,Steve Huijnen,Caroline Jane Magri,Rhizlan Cherradi,Jurriën M. ten Berg,Jan Eritsland,Andrzej Budaj,Carlos Aguiar,Dmitry Duplyakov,Marco Zavatta,Nebojsa M Antonijevic,Zlatko Fras,Antonio Tello Montoliu,Christoph Varenhorst,Dimitri Tsakiris,Faouzi Addad,Sinan Aydogdu,Alexander Parkhomenko,Tim Kinnaird +106 more
TL;DR: The Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed in collaboration with EACTS is described in this paper.
Journal ArticleDOI
2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS
Marco Valgimigli,Héctor Bueno,Robert A. Byrne,Jean-Philippe Collet,Francesco Costa,Anders Jeppsson,Peter Jüni,Adnan Kastrati,Philippe Kolh,Laura Mauri,Gilles Montalescot,Franz-Josef Neumann,Mate Petricevic,Marco Roffi,Philippe Gabriel Steg,Stephan Windecker,José Luis Zamorano,Glenn N. Levine,Lina Badimon,Pascal Vranckx,Stefan Agewall,Felicita Andreotti,Elliott M. Antman,Emanuele Barbato,Jean-Pierre Bassand,Raffaele Bugiardini,Mustafa Cikirikcioglu,Thomas Cuisset,Michele De Bonis,Victora Delgado,Donna Fitzsimons,Oliver Gaemperli,Nazzareno Galiè,Martine Gilard,Christian W. Hamm,Borja Ibanez,Bernard Iung,Stefan James,Juhani Knuuti,Ulf Landmesser,Christophe Leclercq,Maddalena Lettino,Gregory Y.H. Lip,Massimo F Piepoli,Luc Pierard,Markus Schwerzmann,Udo Sechtem,Iain A. Simpson,Miguel Sousa Uva,Eugenio Stabile,Robert F. Storey,Michal Tendera,Frans Van de Werf,Freek W.A. Verheugt,Victor Aboyans +54 more
References
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Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
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TL;DR: Guidelines summarize and evaluate all currently available evidence on a particular issue with the aim of assisting physicians in selecting the best management strategy for an individual patient suffering from a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means.
Journal ArticleDOI
An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.
Maarten L. Simoons,Eric J. Topol,Robert M. Califf,Frans Van de Werf,Paul W. Armstrong,Philip Edmund Aylward,G.I. Barbash,Eric R. Bates,A. Betriu,James Chesebro,J Col,David de Bono,JM Gore,Alan Guerci,John R. Hampton +14 more
TL;DR: The findings of this large-scale trial indicate that accelerated t-PA given with intravenous heparin provides a survival benefit over previous standard thrombolytic regimens.
Journal ArticleDOI
Standardized Bleeding Definitions for Cardiovascular Clinical Trials A Consensus Report From the Bleeding Academic Research Consortium
Roxana Mehran,Sunil V. Rao,Deepak L. Bhatt,C. Michael Gibson,Adriano Caixeta,John W. Eikelboom,Sanjay Kaul,Stephen D. Wiviott,Venu Menon,Eugenia Nikolsky,Victor L. Serebruany,Marco Valgimigli,Pascal Vranckx,David P. Taggart,Joseph F. Sabik,Donald E. Cutlip,Mitchell W. Krucoff,E. Magnus Ohman,Philippe Gabriel Steg,Harvey D. White +19 more
TL;DR: Bleeding complications have been associated with an increased risk of subsequent adverse outcomes, including MI, stroke, stent thrombosis, and death, in patients with ACS and in those undergoing percutaneous coronary intervention (PCI) as well as in the long-term antithrombotic setting.
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Standardized Bleeding Definitions for Cardiovascular Clinical Trials A Consensus Report From the Bleeding Academic Research Consortium
Roxana Mehran,Sunil V. Rao,Deepak L. Bhatt,C. Michael Gibson,Adriano Caixeta,John W. Eikelboom,Sanjay Kaul,Stephen D. Wiviott,Venu Menon,Eugenia Nikolsky,Victor L. Serebruany,Marco Valgimigli,Pascal Vranckx,David P. Taggart,Joseph F. Sabik,Donald E. Cutlip,Mitchell W. Krucoff,E. Magnus Ohman,Philippe Gabriel Steg,Harvey D. White +19 more
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)
Marco Roffi,Carlo Patrono,Jean-Philippe Collet,Christian Mueller,Marco Valgimigli,Felicita Andreotti,Jeroen J. Bax,Michael A. Borger,Carlos Brotons,Derek P. Chew,Baris Gencer,Gerd Hasenfuss,Keld Kjeldsen,Patrizio Lancellotti,Ulf Landmesser,Julinda Mehilli,Debabrata Mukherjee,Robert F. Storey,Stephan Windecker +18 more