Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies.
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...When total exRNA is analyzed, haemolyzed blood products contain higher concentrations of certain RNAs, including miRs-16 and -451 (155)....
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Cites background from "Blood cell origin of circulating mi..."
...If hemolyzed samples are included, the obtained results should be interpreted with care(28) and the degree of hemolysis should be measured.(53)...
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References
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"Blood cell origin of circulating mi..." refers methods in this paper
...additional 12 control arrays were applied to profile serial 2folddilutionsof 30mLofplasma froma singlehealthydonor to determine the analytic measurement ranges for each quantitative PCR assay on the Exiqon array as previously described (7)....
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2,296 citations
1,691 citations
"Blood cell origin of circulating mi..." refers background in this paper
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