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Blood Transfusion and Infection After Cardiac Surgery

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TLDR
Greater attention to management practices that limit RBC use, including cell salvage, small priming volumes, vacuum-assisted venous return with rapid autologous priming, and ultrafiltration, and preoperative and intraoperative measures to elevate hematocrit could potentially reduce occurrence of major postoperative infections.
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This article is published in The Annals of Thoracic Surgery.The article was published on 2013-06-01 and is currently open access. It has received 242 citations till now. The article focuses on the topics: Blood transfusion & Platelet transfusion.

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Health Care–Associated Infection After Red Blood Cell Transfusion: A Systematic Review and Meta-analysis

TL;DR: Among hospitalized patients, a restrictive RBC transfusion strategy was associated with a reduced risk of health care-associated infection compared with a liberal transfusions strategy, suggesting that implementing restrictive strategies may have the potential to lower the incidence of health Care- associated infection.
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Allogeneic Blood Transfusion Increases the Risk of Postoperative Bacterial Infection: A Meta-Analysis: [2002][A-423]

TL;DR: It is demonstrated that allogeneic blood transfusion is a greater risk factor in the traumatically injured patient when compared with the elective surgical patient for the development of postoperative bacterial infection.
References
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Journal ArticleDOI

CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.

TL;DR: In this paper, the NHSN criteria for all healthcare-associated infections (HAIs) are presented, including those for the "Big Four" (surgical site infection [SSI], pneumonia [PNEU], bloodstream infection [BSI] and urinary tract infection [UTI]).
Journal Article

CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.

TL;DR: In this article, the NHSN criteria for all healthcare-associated infections (HAIs) are presented, including those for the "Big Four" (surgical site infection [SSI], pneumonia [PNEU], bloodstream infection [BSI] and urinary tract infection [UTI]).
Journal ArticleDOI

Duration of red-cell storage and complications after cardiac surgery

TL;DR: In patients undergoing cardiac surgery, transfusion of red cells that had been stored for more than 2 weeks was associated with a significantly increased risk of postoperative complications as well as reduced short-term and long-term survival.
Journal ArticleDOI

Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery

TL;DR: Red blood cell transfusion in patients having cardiac surgery is strongly associated with both infection and ischemic postoperative morbidity, hospital stay, increased early and late mortality, and hospital costs.
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