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Journal ArticleDOI

Box-Behnken design based statistical modeling for ultrasound-assisted extraction of corn silk polysaccharide.

30 Jan 2013-Carbohydrate Polymers (Elsevier)-Vol. 92, Iss: 1, pp 604-611
TL;DR: In this study, ultrasound assisted extraction conditions on the yield of polysaccharide from corn silk were studied using three factors, three level Box-Behnken response surface design and optimal conditions based on both individual and combinations of all independent variables were determined.
About: This article is published in Carbohydrate Polymers.The article was published on 2013-01-30. It has received 313 citations till now. The article focuses on the topics: Box–Behnken design & Response surface methodology.
Citations
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Journal ArticleDOI
TL;DR: In this article, the authors discuss the impact of ultrasound-assisted extraction on the recovery of polyphenols, carotenoids and chlorophylls from vegetal and algae matters.
Abstract: Ultrasound treatment is an alternative affordable, effective and reproducible method for the improved recovery of bioactive compounds from various processing streams. The objective of this review is to discuss the impact of ultrasound-assisted extraction on the recovery of polyphenols, carotenoids and chlorophylls from vegetal and algae matters. Optimization strategies will need to focus on appropriate equipment design and configuration of ultrasonic components, and extrinsic and intrinsic control parameters including ultrasonic power, temperature and extraction time to maximize the yield and biological activity of the extract. Modeling strategies to characterize and optimize ultrasound processes are also be highlighted in the manuscript.

295 citations

Journal ArticleDOI
TL;DR: From the results, second order polynomial model was developed and it adequately explained the data variation and significantly represented the actual relationship between independent variables and the response.

245 citations


Cites methods from "Box-Behnken design based statistica..."

  • ...The range of independent variables and heir levels are presented in Table 1 and it was coded (−1, 0 and 1) according to the method described by Prakash Maran et al. 2013) for statistical calculation....

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Journal ArticleDOI
TL;DR: The predicted values were in correlation with experimental values with 95% confidence level, under the determined optimal conditions, indicating the significance of selected method for USLE of phytochemicals from SCG.

224 citations

Journal ArticleDOI
TL;DR: The developed formulations did not show any toxicity and were safe for intranasal delivery for brain targeting and in vitro diffusion studies revealed that nanoemulsions had a significantly higher release compared to drug solution.

210 citations

Journal ArticleDOI
TL;DR: In this paper, four factors at three level central composite face centered design were employed to study and optimize the process variables on extraction of bioactive compounds (total anthocyanin, phenolic and flavonoid content) from Nephelium lappaceum L. fruit peel.

203 citations


Cites background or methods from "Box-Behnken design based statistica..."

  • ...These graphs are drawn by maintaining two factors constant (in turn at its central level) and varying the other two factors in order to understand their main and interactive effects on the dependent variables (Prakash Maran et al., 2013)....

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  • ...The coding of the variables was done by the following equation (Prakash Maran et al., 2013): xi ¼ Xi Xz DXi i ¼ 1; 2; 3 . . . k ð3Þ where xi, is the dimensionless value of an independent variable; Xi, the real value of an independent variable; Xz, the real value of an independent variable at the…...

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  • ...In general, the exploration of fitted response surface models may produce poor or misleading results, unless the model exhibits a good fit, which makes checking of the model adequacy essential (Prakash Maran et al., 2013a)....

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  • ...…variables (i and j range from 1 to k); b0 is the model intercept coefficient; bj, bjj and bij are interaction coefficients of linear, quadratic and the secondorder terms, respectively; k is the number of independent parameters (k= 4 in this study); and ei is the error (Prakash Maran et al., 2013)....

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  • ...Adequate precision is greater than four is desirable (Prakash Maran et al., 2013b) and the ratio was found to be >95, which indicates an adequate signal and confirms that this model can be used to navigate the design space....

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References
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Journal ArticleDOI
TL;DR: In this article, the authors present a set of conditions that will result in a product with a desirable combination of properties, which is a problem facing the product development community in general.
Abstract: A problem facing the product development community is the selection of a set of conditions which will result in a product with a desirable combination of properties. This essentially is a problem i...

4,109 citations

Journal ArticleDOI
TL;DR: In this paper, a class of incomplete three level factorial designs useful for estimating the coefficients in a second degree graduating polynomial are described and the designs either meet, or approximately meet, the criterion of rotatability and for the most part can be orthogonally blocked.
Abstract: A class of incomplete three level factorial designs useful for estimating the coefficients in a second degree graduating polynomial are described. The designs either meet, or approximately meet, the criterion of rotatability and for the most part can be orthogonally blocked. A fully worked example is included.

3,194 citations

Journal ArticleDOI
Mircea Vinatoru1
TL;DR: This paper presents a review of the ultrasonically assisted extraction of bioactive principles from herbs under European community grants under the COPERNICUS programme and in a COST D10 network.

991 citations

Journal ArticleDOI
TL;DR: A series of experiments has been developed to investigate the effect of ultrasonic energy on the vegetal material and the solvent used and several results concerning the ultrasonic extractive value, ultrasonic swelling index and the effects of frequency on Vegetal material are presented.

554 citations

Journal ArticleDOI
TL;DR: The efficiency of the extraction of soy isoflavones was improved by ultrasound but was dependent on the solvent employed, and the ratios of sample quantity to solvent volume and length of extraction time were improved.

496 citations