Branch duct intraductal papillary mucinous neoplasms: does cyst size change the tip of the scale? A critical analysis of the revised international consensus guidelines in a large single-institutional series.
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Cites background or methods from "Branch duct intraductal papillary m..."
...While it has been reported that ~10% “malignant” BD IPMNs have no mural nodules, nearly all of these ca ses were HGD [19, 81, 108], and thus invasive cancer is exceptional in the absence of a mural nod ule within the cyst....
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...The usefulness of the previous Fukuoka consensus cr iteria for resections has been validated by many reports [81-87, 94-102]....
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...Although cyst size is associated with an increased risk of harboring HGD and invasive cancer, there is no cut-off to quantify the risk [85, 120], and i n general, cyst size alone is not an appropriate parameter to indicate surgery given its poor predic tive value for invasive carcinoma and HGD [19, 76, 81, 121-123]....
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Cites background from "Branch duct intraductal papillary m..."
...Similarly, over 75% of resected IPMNs harbor only low-, or intermediate-grade dysplasia, and these also could have been safely observed.(10)...
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222 citations
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