Breaking the 10 nm barrier in hard-X-ray focusing
TL;DR: In this paper, an in situ technique that corrects for wavefront aberrations and allows X-rays to be focused to a spot just 7 nm wide could provide a solution.
Abstract: X-ray sources such as free-electron lasers offer the potential to study matter at unprecedented spatial and temporal resolution. But that potential is limited by the poor quality of conventional X-ray optical elements. An in situ technique that corrects for wavefront aberrations and allows X-rays to be focused to a spot just 7 nm wide could provide a solution.
Citations
More filters
TL;DR: In this article, a review of recent investigations on high-energy processes within the realm of relativistic quantum dynamics, quantum electrodynamics, and nuclear and particle physics, occurring in extremely intense laser fields is presented.
Abstract: The field of laser-matter interaction traditionally deals with the response of atoms, molecules, and plasmas to an external light wave. However, the recent sustained technological progress is opening up the possibility of employing intense laser radiation to trigger or substantially influence physical processes beyond atomic-physics energy scales. Available optical laser intensities exceeding ${10}^{22}\text{ }\text{ }\mathrm{W}/{\mathrm{cm}}^{2}$ can push the fundamental light-electron interaction to the extreme limit where radiation-reaction effects dominate the electron dynamics, can shed light on the structure of the quantum vacuum, and can trigger the creation of particles such as electrons, muons, and pions and their corresponding antiparticles. Also, novel sources of intense coherent high-energy photons and laser-based particle colliders can pave the way to nuclear quantum optics and may even allow for the potential discovery of new particles beyond the standard model. These are the main topics of this article, which is devoted to a review of recent investigations on high-energy processes within the realm of relativistic quantum dynamics, quantum electrodynamics, and nuclear and particle physics, occurring in extremely intense laser fields.
1,394 citations
Book•
30 Apr 2020TL;DR: In this paper, the fundamental properties of soft x-rays and extreme ultraviolet (EUV) radiation are discussed and their applications in a wide variety of fields, including EUV lithography for semiconductor chip manufacture and soft X-ray biomicroscopy.
Abstract: This self-contained, comprehensive book describes the fundamental properties of soft x-rays and extreme ultraviolet (EUV) radiation and discusses their applications in a wide variety of fields, including EUV lithography for semiconductor chip manufacture and soft x-ray biomicroscopy. The author begins by presenting the relevant basic principles such as radiation and scattering, wave propagation, diffraction, and coherence. He then goes on to examine a broad range of phenomena and applications. The topics covered include EUV lithography, biomicroscopy, spectromicroscopy, EUV astronomy, synchrotron radiation, and soft x-ray lasers. He also provides a great deal of useful reference material such as electron binding energies, characteristic emission lines and photo-absorption cross-sections. The book will be of great interest to graduate students and researchers in engineering, physics, chemistry, and the life sciences. It will also appeal to practicing engineers involved in semiconductor fabrication and materials science.
786 citations
TL;DR: A review of recent work in the development of direct image-forming X-ray microscopy techniques and the relevant applications can be found in this article, including three-dimensional biological tomography, dynamical processes in magnetic nanostructures, chemical speciation studies, industrial applications related to solar cells and batteries, and studies of archaeological materials.
Abstract: Recent years have seen significant progress in the field of soft- and hard-X-ray microscopy, both technically, through developments in source, optics and imaging methodologies, and also scientifically, through a wide range of applications While an ever-growing community is pursuing the extensive applications of today's available X-ray tools, other groups are investigating improvements in techniques, including new optics, higher spatial resolutions, brighter compact sources and shorter-duration X-ray pulses This Review covers recent work in the development of direct image-forming X-ray microscopy techniques and the relevant applications, including three-dimensional biological tomography, dynamical processes in magnetic nanostructures, chemical speciation studies, industrial applications related to solar cells and batteries, and studies of archaeological materials and historical works of art
567 citations
TL;DR: This review focuses on recent developments of nanoscintillators with high energy transfer efficiency, their rational designs, as well as potential applications in next-generation PDT.
Abstract: Achieving effective treatment of deep-seated tumors is a major challenge for traditional photodynamic therapy (PDT) due to difficulties in delivering light into the subsurface. Thanks to their great tissue penetration, X-rays hold the potential to become an ideal excitation source for activating photosensitizers (PS) that accumulate in deep tumor tissue. Recently, a wide variety of nanoparticles have been developed for this purpose. The nanoparticles are designed as carriers for loading various kinds of PSs and can facilitate the activation process by transferring energy harvested from X-ray irradiation to the loaded PS. In this review, we focus on recent developments of nanoscintillators with high energy transfer efficiency, their rational designs, as well as potential applications in next-generation PDT. Treatment of deep-seated tumors by using radioisotopes as an internal light source will also be discussed.
269 citations
TL;DR: How submicrometer hard x-ray beams with the ability to penetrate tens to hundreds of micrometers into most materials and with the able to determine local composition, chemistry, and (crystal) structure can characterize buried sample volumes and small samples in their natural or extreme environments is described.
Abstract: X-ray microbeams are an emerging characterization tool with broad implications for science, ranging from materials structure and dynamics, to geophysics and environmental science, to biophysics and protein crystallography. We describe how submicrometer hard x-ray beams with the ability to penetrate tens to hundreds of micrometers into most materials and with the ability to determine local composition, chemistry, and (crystal) structure can characterize buried sample volumes and small samples in their natural or extreme environments. Beams less than 10 nanometers have already been demonstrated, and the practical limit for hard x-ray beam size, the limit to trace-element sensitivity, and the ultimate limitations associated with near-atomic structure determinations are the subject of ongoing research.
266 citations
References
More filters
TL;DR: In this paper, it was shown that the extraction of gauge invariants from a formally gauge invariant theory is ensured if one employs methods of solution that involve only gauge covariant quantities.
Abstract: This paper is based on the elementary remark that the extraction of gauge invariant results from a formally gauge invariant theory is ensured if one employs methods of solution that involve only gauge covariant quantities. We illustrate this statement in connection with the problem of vacuum polarization by a prescribed electromagnetic field. The vacuum current of a charged Dirac field, which can be expressed in terms of the Green's function of that field, implies an addition to the action integral of the electromagnetic field. Now these quantities can be related to the dynamical properties of a "particle" with space-time coordinates that depend upon a proper-time parameter. The proper-time equations of motion involve only electromagnetic field strengths, and provide a suitable gauge invariant basis for treating problems. Rigorous solutions of the equations of motion can be obtained for a constant field, and for a plane wave field. A renormalization of field strength and charge, applied to the modified lagrange function for constant fields, yields a finite, gauge invariant result which implies nonlinear properties for the electromagnetic field in the vacuum. The contribution of a zero spin charged field is also stated. After the same field strength renormalization, the modified physical quantities describing a plane wave in the vacuum reduce to just those of the maxwell field; there are no nonlinear phenomena for a single plane wave, of arbitrary strength and spectral composition. The results obtained for constant (that is, slowly varying fields), are then applied to treat the two-photon disintegration of a spin zero neutral meson arising from the polarization of the proton vacuum. We obtain approximate, gauge invariant expressions for the effective interaction between the meson and the electromagnetic field, in which the nuclear coupling may be scalar, pseudoscalar, or pseudovector in nature. The direct verification of equivalence between the pseudoscalar and pseudovector interactions only requires a proper statement of the limiting processes involved. For arbitrarily varying fields, perturbation methods can be applied to the equations of motion, as discussed in Appendix A, or one can employ an expansion in powers of the potential vector. The latter automatically yields gauge invariant results, provided only that the proper-time integration is reserved to the last. This indicates that the significant aspect of the proper-time method is its isolation of divergences in integrals with respect to the proper-time parameter, which is independent of the coordinate system and of the gauge. The connection between the proper-time method and the technique of "invariant regularization" is discussed. Incidentally, the probability of actual pair creation is obtained from the imaginary part of the electromagnetic field action integral. Finally, as an application of the Green's function for a constant field, we construct the mass operator of an electron in a weak, homogeneous external field, and derive the additional spin magnetic moment of $\frac{\ensuremath{\alpha}}{2\ensuremath{\pi}}$ magnetons by means of a perturbation calculation in which proper-mass plays the customary role of energy.
5,579 citations
"Breaking the 10 nm barrier in hard-..." refers background in this paper
...can be expected to produce a highly localized electromagnetic field strong enough to overcome the Schwinger limi...
[...]
TL;DR: Iterative algorithms for phase retrieval from intensity data are compared to gradient search methods and it is shown that both the error-reduction algorithm for the problem of a single intensity measurement and the Gerchberg-Saxton algorithm forThe problem of two intensity measurements converge.
Abstract: Iterative algorithms for phase retrieval from intensity data are compared to gradient search methods. Both the problem of phase retrieval from two intensity measurements (in electron microscopy or wave front sensing) and the problem of phase retrieval from a single intensity measurement plus a non-negativity constraint (in astronomy) are considered, with emphasis on the latter. It is shown that both the error-reduction algorithm for the problem of a single intensity measurement and the Gerchberg-Saxton algorithm for the problem of two intensity measurements converge. The error-reduction algorithm is also shown to be closely related to the steepest-descent method. Other algorithms, including the input-output algorithm and the conjugate-gradient method, are shown to converge in practice much faster than the error-reduction algorithm. Examples are shown.
5,210 citations
"Breaking the 10 nm barrier in hard-..." refers methods in this paper
...The iterative algorithm is based on the nonlinear optimizatio...
[...]
TL;DR: In this paper, the authors used three-dimensional particle-in-cell simulations to study laser wake field acceleration (LWFA) at highly relativistic laser intensities, and observed ultra-short electron bunches emerging from laser wake fields driven above the wave-breaking threshold by few-cycle laser pulses shorter than the plasma wavelength.
Abstract: We use three-dimensional particle-in-cell simulations to study laser wake field acceleration (LWFA) at highly relativistic laser intensities. We observe ultra-short electron bunches emerging from laser wake fields driven above the wave-breaking threshold by few-cycle laser pulses shorter than the plasma wavelength. We find a new regime in which the laser wake takes the shape of a solitary plasma cavity. It traps background electrons continuously and accelerates them. We show that 12-J, 33-fs laser pulses may produce bunches of 3×1010 electrons with energy sharply peaked around 300 MeV. These electrons emerge as low-emittance beams from plasma layers just 700-μm thick. We also address a regime intermediate between direct laser acceleration and LWFA, when the laser-pulse duration is comparable with the plasma period.
1,055 citations
TL;DR: The technique of atom probe tomography is reviewed with an emphasis on illustrating what is possible with the technique both now and in the future, and how to fabricate suitable specimens from new classes of materials.
Abstract: The technique of atom probe tomography (APT) is reviewed with an emphasis on illustrating what is possible with the technique both now and in the future. APT delivers the highest spatial resolution (sub-0.3-nm) three-dimensional compositional information of any microscopy technique. Recently, APT has changed dramatically with new hardware configurations that greatly simplify the technique and improve the rate of data acquisition. In addition, new methods have been developed to fabricate suitable specimens from new classes of materials. Applications of APT have expanded from structural metals and alloys to thin multilayer films on planar substrates, dielectric films, semiconducting structures and devices, and ceramic materials. This trend toward a broader range of materials and applications is likely to continue.
816 citations
Book•
01 Jan 2000TL;DR: In this paper, a focused ion beam milling system was used for atom probe tomography for the characterization of the size, morphology and composition of ultrafine features in a variety of materials.
Abstract: Atom probe tomography is a powerful tool for the characterization of the size, morphology and composition of ultrafine features in a variety of materials. With the development of new forms of specimen preparation especially with focused ion beam milling systems, atom probe tomography should be extended to a wider variety of applications in nanotechnology.
627 citations