Building a lineage from single cells: genetic techniques for cell lineage tracking.
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Cites background from "Building a lineage from single cell..."
...Joint measures with the emerging repertoire of CRISPR-based tools for lineage tracing (Woodworth et al., 2017) will be essential for quantifying the epigenomic contribution of lineage priming on cell fate decisions over time....
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Cites background from "Building a lineage from single cell..."
...Lineage maps are key to understanding and controlling differentiation (2)....
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...This approach can map the fate of cells from a continuous landscape of starting states and does not require isolation or labeling of specific prospective progenitor populations (2, 14)....
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...Unlike lineage tracing, scSeq can be performed without prior genetic manipulation and without being limited by the specificity of transgene expression within the progenitor cell pool (2)....
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References
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