Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model.
Citations
1,708 citations
Cites background from "Butyrate-producing Clostridium clus..."
...H. et al. (2014) Characterization of the gut microbiota in leptin deficient obese mice - correlation to inflammatory and diabetic parameters....
[...]
...H. et al. (2016) The mucin-degradation strategy of ruminococcus gnavus: The importance of intramolecular trans-sialidases....
[...]
..., Sjövall, H. et al. (2011) Altered o-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation....
[...]
1,344 citations
1,004 citations
905 citations
774 citations
Cites background from "Butyrate-producing Clostridium clus..."
...specifically colonize mucus (37), and for some, growth on mucus-...
[...]
References
11,380 citations
"Butyrate-producing Clostridium clus..." refers methods in this paper
...Quantification of these groups has been validated with fluorescence in situ hybridization, quantitative PCR and 454 pyrosequencing (Rajilic-Stojanovic et al., 2009; Claesson et al., 2011; van den Bogert et al., 2011)....
[...]
...PCR products were cut from a gel, purified (QIAquick Gel Extraction Kit, QIAGEN, Antwerp, Belgium) and cloned with a TOPO TA Cloning Kit with pCR2....
[...]
...After DNA extraction (Boon et al., 2003) and PCR (Muyzer et al., 1993), gels were run using an Ingeny PhorU apparatus (Ingeny International, Goes, The Netherlands)....
[...]
10,126 citations
"Butyrate-producing Clostridium clus..." refers background in this paper
...Furthermore, the importance of the intestinal mcrobiota follows from the number of diseases that have been correlated with a dysbiosed microbial composition, such as inflammatory bowel diseases (IBDs; Willing et al., 2009; Walker et al., 2011) or obesity (Turnbaugh et al., 2006)....
[...]
7,049 citations
"Butyrate-producing Clostridium clus..." refers background in this paper
..., 2004), also impact the distinct surface-attached microbial composition, generally characterized by an enrichment of Firmicutes (especially Clostridium cluster XIVa) over Bacteroidetes (Eckburg et al., 2005; Frank et al., 2007; Hill et al., 2009; Shen et al., 2010; Willing et al., 2010; Hong et al., 2011; Nava et al., 2011)....
[...]
...The human colon is colonized by a complex microbiota, mostly (490%) consisting of Bacteroidetes and Firmicutes (Eckburg et al., 2005; Claesson et al., 2011; Walker et al., 2011)....
[...]
...%) consisting of Bacteroidetes and Firmicutes (Eckburg et al., 2005; Claesson et al., 2011; Walker et al., 2011)....
[...]
...…cluster XIVa4 Lachnospiraceae family), over Bacteroidetes in biopsies compared with luminal or faecal samples, both in rodents (Hill et al., 2009; Nava et al., 2011) and humans (Eckburg et al., 2005; Frank et al., 2007; Shen et al., 2010; Wang et al., 2010; Willing et al., 2010; Hong et al., 2011)....
[...]
...…we confirm the inter-individual differences in microbiota composition among different human stool and mucosal samples (Zoetendal et al., 1998, 2002; Eckburg et al., 2005) and demonstrate that these microbial patterns unique to each individual are preserved in the luminal and mucosal in vitro…...
[...]
4,526 citations
"Butyrate-producing Clostridium clus..." refers background in this paper
...Beneficial contributions of this microbiota to human health include the breakdown of otherwise indigestible food compounds (Koropatkin et al., 2012) and regulation of host metabolism (Backhed et al., 2005)....
[...]
..., 2012) and regulation of host metabolism (Backhed et al., 2005)....
[...]
3,967 citations