Journal ArticleDOI
Cadmium-induced antioxidant defense mechanism in freshwater teleost Oreochromis mossambicus (Tilapia).
P.Siraj Basha,A. Usha Rani +1 more
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TLDR
The findings indicate that tissue glutathione-dependent enzymes as well as other antioxidant enzymes function in protection against Cd2+ toxicity and that these antioxidants provide a first line of defense against C d2+ before the induction of any metallothionein synthesis occurs.About:
This article is published in Ecotoxicology and Environmental Safety.The article was published on 2003-10-01. It has received 372 citations till now. The article focuses on the topics: Glutathione peroxidase & Superoxide dismutase.read more
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Antioxidant Defenses in Fish: Biotic and Abiotic Factors
TL;DR: This review investigates the influence of different biotic and abiotic factors (age, phylogenetic position, feeding behavior, environmental factors, oxygen, temperature, presence of xenobiotics) on antioxidant defenses in fish.
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Bioaccumulation of heavy metals in organs of fresh water fish Cyprinus carpio (Common carp)
R. Vinodhini,M. Narayanan +1 more
TL;DR: In this paper, the authors determined the bioaccumulation of heavy metals in various organs of the fresh water fish exposed to heavy metal contaminated water system for a period of 32 days and found that the accumulation of heavy metal gradually increases in liver during the heavy metal exposure period.
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Oxidative stress biomarkers in the freshwater characid fish, Brycon cephalus, exposed to organophosphorus insecticide Folisuper 600 (methyl parathion)
TL;DR: The current data suggest that MPc has oxidative-stress-inducing potential in fish, and that gills and white muscle are the most sensitive organs of B. cephalus, with poor antioxidant potentials.
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Use of Fish as Bio-indicator of the Effects of Heavy Metals Pollution
TL;DR: In this article, a review of the toxic effects of heavy metals on fish is given, where some recommendations are given to treatment of different kinds of wastewaters, sewage and agricultural wastes before discharge into the aquatic systems.
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Response of catalase activity to Ag+, Cd2+, Cr6+, Cu2+ and Zn2+ in five tissues of freshwater fish Oreochromis niloticus.
TL;DR: Results emphasized that CAT may be considered as a sensitive bioindicator of the antioxidant defense system and significantly inhibited the CAT activity in all tissues.
References
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Journal ArticleDOI
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
TL;DR: The purification of homogeneous glutathione S-transferases B and C from rat liver is described, and only transferases A and C are immunologically related.
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Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels☆
TL;DR: The staining procedure for localizing superoxide dismutase on polyacrylamide electrophoretograms has been applied to extracts obtained from a variety of sources and could thus be assayed either in crude extracts or in purified protein fractions.
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Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
TL;DR: Glutathione peroxidase activity is found to be associated with a relatively stable, nondialyzable, heat-labile, intracellular component which is separable from hemoglobin, by gel filtration and ammonium sulfate precipitation.
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Glutathione peroxidase activity in selenium-deficient rat liver☆
TL;DR: Two peaks of glutathione peroxidase activity were present in the Sephadex G-150 gel filtration chromatogram of rat liver supernatant when 1.5 mM cumene hydroperoxide was used as substrate, and the second peak represents a second glutathienase activity which catalyzes the destruction of organic hydroperoxides but has little activity toward H 2 O 2 and which persists in severe selenium deficiency.
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Oxidative Stress as a Mechanism of Chronic Cadmium-Induced Hepatotoxicity and Renal Toxicity and Protection by Antioxidants☆☆☆★
TL;DR: In this article, the role of oxidative stress in chronic cadmium toxicity and its prevention by cotreatment with antioxidants was investigated, and a Japanese hepatoprotective drug, Stronger Neo-Minophagen C, containing glycyrrhizin, glycine, and cysteine, was also effective in reducing the chronic Cd nephrotoxicity.