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Journal ArticleDOI

Caffeine fatalities—four case reports

Per Holmgren, +2 more
- 06 Jan 2004 - 
- Vol. 139, Iss: 1, pp 71-73
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TLDR
It seems to be warranted to include caffeine in the drug-screening of forensic autopsy cases, although it is not motivated from a medical point of view to sell pure caffeine over the counter.
About
This article is published in Forensic Science International.The article was published on 2004-01-06. It has received 134 citations till now. The article focuses on the topics: Poison control.

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Citations
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Journal ArticleDOI

Health Effects of Energy Drinks on Children, Adolescents, and Young Adults

TL;DR: Energy drinks have no therapeutic benefit, and many ingredients are understudied and not regulated, and concerns for potentially serious adverse effects in association with energy drink use are raised.
Journal ArticleDOI

Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug?

TL;DR: The present review summarizes the main findings concerning caffeine’s mechanisms of action, use, abuse, dependence, intoxication, and lethal effects, and suggests that the concepts of toxic and lethal doses are relative.
Journal ArticleDOI

Safety issues associated with commercially available energy drinks

TL;DR: The amounts of guarana, taurine, and ginseng found in popular energy drinks are far below the amounts expected to deliver either therapeutic benefits or adverse events, however, caffeine and sugar are present in amounts known to cause a variety of adverse health effects.
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Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children

TL;DR: The evidence generally supports that consumption of up to 400 mg caffeine/day in healthy adults is not associated with overt, adverse cardiovascular effects, behavioral effects, reproductive and developmental effects, acute effects, or bone status and a shift in caffeine research to focus on characterizing effects in sensitive populations is supported.
References
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Journal Article

Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use

TL;DR: Caffeine is the most widely consumed behaviorally active substance in the world and almost all caffeine comes from dietary sources (beverages and food).
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Dose-Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans

TL;DR: While favorable subjective and performance‐enhancing stimulant effects occur at low to intermediate caffeine doses, the unfavorable subjective and somatic effects, as well as performance disruption, from high doses of caffeine may intrinsically limit the doses of caffeine used in the general population.
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Drug and chemical blood-level data 2001.

TL;DR: Current blood-level data are presented for drugs and chemicals of toxicologic interest and represent an update of previously published compilations of therapeutic, toxic and lethal blood-levels.
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A compilation of fatal and control concentrations of drugs in postmortem femoral blood.

TL;DR: The data gathered from cases with other cause of death than intoxication constitute a new kind of reference information, which probably offers a better estimate of obviously non fatal levels in postmortem blood than any compilation of therapeutic concentrations in living subjects.
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