Calcitonin Gene-Related Peptide and Its Receptors: Molecular Genetics, Physiology, Pathophysiology, and Therapeutic Potentials
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1,752 citations
Cites background from "Calcitonin Gene-Related Peptide and..."
...Further, CGRP may enhance the release of GLU and SP from PAF terminals (Kangrga and Randic, 1990; Schaible et al., 1992; Wimalawansa, 1996)....
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...In addition, an increase in NO synthesis, leading to the formation of PKG, may be involved (Sluka and Willis, 1997; Wimalawansa, 1996)....
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780 citations
759 citations
Cites background from "Calcitonin Gene-Related Peptide and..."
...Perivascular nerves have been suggested to be a major source of plasma CGRP, that has been found to become deficient in certain types of hypertension (86, 367, 435)....
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...The role of CGRP remains unclear, despite excellent and previous reviews including (28, 41, 86, 430, 435)....
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...The cardiovascular activity of CGRP has previously been reviewed extensively (28, 41, 86, 267, 329, 367, 430, 435)....
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...When CGRP was administered systemically, it reduced the BP in both normotensive and hypertensive rats (132, 198, 435)....
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702 citations
672 citations
Cites background from "Calcitonin Gene-Related Peptide and..."
...CGRP is a cyclic peptide (with a disulfide bond between Cys2 and Cys7) of 37 amino acids (see Wimalawansa, 1996 for review)....
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