CancerTracer: a curated database for intrapatient tumor heterogeneity.
Citations
2,019 citations
318 citations
Cites background from "CancerTracer: a curated database fo..."
...Wang,C., Yang,J., Luo,H., Wang,K., Wang,Y., Xiao,Z.-X., Tao,X., Jiang,H. and Cai,H. (2020) CancerTracer: a curated database for intrapatient tumor heterogeneity....
[...]
...Existing data clients include GeneCards (8), BioGPS (9), CancerTracer (10), Gene4Denovo (11), SLBioDP (12), TargetDB (13) and OncoGemini (14), among others....
[...]
67 citations
Cites background from "CancerTracer: a curated database fo..."
...As ever, cancer databases are well-represented with new contributions to the field including CancerTracer (81), a resource for studying and intrapatient tumor heterogeneity that features data from 1500 patients, including patient-specific tumor phylogenetic trees, and DNMIVD (82) which has a wide range of functions regarding links between DNA methylation and cancer....
[...]
32 citations
26 citations
References
51,099 citations
"CancerTracer: a curated database fo..." refers background in this paper
...The process of conversion from a normal to a malignant cell is known to occur through the sequential accumulation of alterations in oncogenes and tumor suppressor genes (4,5)....
[...]
32,980 citations
Additional excerpts
...All terms pairs with Kappa similarity >0.3 were connected and visualized by Cytoscape (60)....
[...]
...3 were connected and visualized by Cytoscape (60)....
[...]
29,504 citations
11,571 citations
"CancerTracer: a curated database fo..." refers methods in this paper
...To systematically annotate the functional impact of somatic mutations in proteins, we employed ANNOVAR (46) and PolyPhen2 (47) to perform the analysis....
[...]
...The annotations from SIFT, PolyPhen2, etc., as well as protein change, were displayed in the table....
[...]
...About 88.78% mutations were successfully annotated by ANNOVAR or PolyPhen2, and 84.62% of non-synonymous point mutations were annotated by SIFT and/or PolyPhen2....
[...]
10,461 citations
"CancerTracer: a curated database fo..." refers methods in this paper
...To systematically annotate the functional impact of somatic mutations in proteins, we employed ANNOVAR (46) and PolyPhen2 (47) to perform the analysis....
[...]
...We also provide systematic annotation on the curated somatic mutations by ANNOVAR....
[...]
...About 88.78% mutations were successfully annotated by ANNOVAR or PolyPhen2, and 84.62% of non-synonymous point mutations were annotated by SIFT and/or PolyPhen2....
[...]