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Cellular and Molecular Immunology

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Cellular and molecular immunology , Cellular and molecular Immunology , کتابخانه الکرونیک و دیجیتال - آذرسا
Abstract
Cellular and molecular immunology , Cellular and molecular immunology , کتابخانه الکترونیک و دیجیتال - آذرسا

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Journal ArticleDOI

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

TL;DR: Progression of COPD is associated with the accumulation of inflammatory mucous exudates in the lumen and infiltration of the wall by innate and adaptive inflammatory immune cells that form lymphoid follicles, coupled to a repair or remodeling process that thickens the walls of these airways.
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Social Support and Health: A Review of Physiological Processes Potentially Underlying Links to Disease Outcomes

TL;DR: Evidence linking social support to changes in cardiovascular, neuroendocrine, and immune function and related to more positive “biological profiles” across these disease-relevant systems is examined.
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DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

TL;DR: By far the most efficient DNA immunizations were achieved by using a gene gun to deliver DNA-coated gold beads to the epidermis, and 95% protection was achieved by two immunizations with beads loaded with as little as 0.4 micrograms of DNA.
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Pathophysiology of airflow limitation in chronic obstructive pulmonary disease

TL;DR: The technology needed to diagnose and quantitate the individual small airway and emphysema phenotypes present in people with COPD is being developed, and should prove helpful in the assessment of therapeutic interventions designed to modify the progress of either phenotype.
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IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

TL;DR: It is suggested that therapeutic inhibition of IFN-gamma signaling may lead to the formation of more lipid-poor and stable atheromata, and promotes and modifies atherosclerosis through both local effects in the arterial wall as well as a systemic effect on plasma lipoproteins.