Journal ArticleDOI
Cellular circadian clocks in the pineal.
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This review focuses on the functional properties of the cellular circadian clocks of non-mammalian vertebrates and how functions the clock?About:
This article is published in Progress in Neurobiology.The article was published on 1999-06-01. It has received 295 citations till now. The article focuses on the topics: Light effects on circadian rhythm & Circadian clock.read more
Citations
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Journal ArticleDOI
Current knowledge on the melatonin system in teleost fish
TL;DR: How manipulation of the photic cues impact on fish circannual clock and annual cycle of reproduction, and how this can be used for aquaculture purposes is discussed.
Journal ArticleDOI
The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain
TL;DR: The neuroanatomy of the DDC is described, its physiology and behavioural involvement is considered, examples of neural asymmetries within both habenular circuitry and the pineal complex are discussed, and studies in zebrafish are discussed.
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Reduced oxidative damage in ALS by high-dose enteral melatonin treatment.
Jochen H. Weishaupt,Claudia Bartels,Esther Polking,Jeannine Dietrich,Gundula Rohde,Burkhard Poeggeler,Nina Mertens,Swetlana Sperling,Matthias Bohn,Gerald Hüther,Armin Schneider,Bach Alfred,Anna-Leena Sirén,Rüdiger Hardeland,Mathias Bähr,Klaus-Armin Nave,Hannelore Ehrenreich +16 more
TL;DR: It is found that melatonin attenuates glutamate‐induced cell death of cultured motoneurons and suggests that high‐dose melatonin is suitable for clinical trials aimed at neuroprotection through antioxidation in ALS.
Journal ArticleDOI
Asymmetry in the epithalamus of vertebrates
TL;DR: The epithalamus is a major subdivision of the diencephalon constituted by the habenular nuclei and pineal complex and Connectivity of the parapineal organ with the left habenula is not always coupled with asymmetries in ha benular size and/or neuronal organisation suggesting that, at least in some species, assignment of parapineAL and habenul asymmetry may be independent events.
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Current knowledge on the photoneuroendocrine regulation of reproduction in temperate fish species
TL;DR: This review aims to bring together the current knowledge on the photic control of reproduction mainly focusing on seasonal temperate fish species and shape the current working hypotheses supported by recent findings obtained in teleosts or based on knowledge gathered in mammalian and avian species.
References
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Journal ArticleDOI
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
Nicholas Gekakis,David Staknis,David Staknis,David Staknis,Hubert B. Nguyen,Hubert B. Nguyen,Hubert B. Nguyen,Fred C. Davis,Fred C. Davis,Fred C. Davis,Lisa D. Wilsbacher,Lisa D. Wilsbacher,Lisa D. Wilsbacher,David P. King,David P. King,David P. King,Joseph S. Takahashi,Joseph S. Takahashi,Joseph S. Takahashi,Charles J. Weitz,Charles J. Weitz,Charles J. Weitz +21 more
TL;DR: CLOCK-BMAL1 heterodimers appear to drive the positive component of per transcriptional oscillations, which are thought to underlie circadian rhythmicity.
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Isolation of melatonin, the pineal gland factor that lightens melanocytes1
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Mutagenesis and Mapping of a Mouse Gene, Clock, Essential for Circadian Behavior
Martha Hotz Vitaterna,David P. King,Anne Marie Chang,Jon M. Kornhauser,Phillip L. Lowrey,J. David McDonald,J. David McDonald,William F. Dove,Lawrence H. Pinto,Fred W. Turek,Joseph S. Takahashi +10 more
TL;DR: The power of ENU mutagenesis combined with the ability to clone murine genes by map position provides a generally applicable approach to study complex behavior in mammals.
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Positional cloning of the mouse circadian clock gene.
David P. King,Yaliang Zhao,Ashvin M. Sangoram,Lisa D. Wilsbacher,Minoru Tanaka,Marina P. Antoch,Thomas D.L. Steeves,Martha Hotz Vitaterna,Jon M. Kornhauser,Jon M. Kornhauser,Phillip L. Lowrey,Fred W. Turek,Joseph S. Takahashi +12 more
TL;DR: CLOCK represents the second example of a PAS domain-containing clock protein (besides Drosophila PERIOD), which suggests that this motif may define an evolutionarily conserved feature of the circadian clock mechanism.