Cellular defenses against damage from reactive oxygen species
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...Antioxidants defense systems co-evolved along with aerobic metabolism to counteract oxidative damage from OFR [92]....
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...Cells exposed to environment *Address correspondence to these authors at the Department of Biotechnology, M. J. College, M. J. Road, Jalgaon- 425 001, India; Tel: +91 0257 2234281- 32; Fax: +91 0257 2237363; E-mail: rt_mahajan@rediffmail.com Tel: +91 02582 247702; E-mail: uttarabayani@yahoo.com #These authors contributed equally to this review. fortified with oxygen continuously generate oxygen free radicals (OFR)....
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...Interestingly, serum has antioxidant activity (Yu, 1994), and, consistently, NET formation is inhibited in a concentration-dependent fashion by serum (Fig....
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...First, GSH can directly react with a variety of radicals by donating a hydrogen atom (414)....
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...inant form existing at physiological pH (414)....
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