Cerebral Venous Sinus Thrombosis as an Unexpected Complication of COVID-19 Pneumonia
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In this article, the authors present a rare case of a young patient with COVID-19 who presented with thrombosis of the cerebral venous system managed with anticoagulation.Abstract:
Coronavirus disease 2019 (COVID-19) is commonly associated with acute respiratory distress syndrome and acute cardiac and renal injuries. However, thromboembolic events are also prevalent in COVID-19. The pathogenesis of COVID-19 hypercoagulability is not well known but may be linked to the cytokine storm induced by a viral infection or endothelial damage that triggers a cascade leading to hypercoagulability. Because vascular endothelium has angiotensin-converting enzyme 2-like lung tissue, COVID-19 targets lung tissue and vascular endothelium, leading to thrombosis. We present a rare case of a young patient with COVID-19 who presented with thrombosis of the cerebral venous system managed with anticoagulation. This case highlights the need for heightened awareness of this atypical but potentially treatable complication of the COVID-19 disease spectrum.read more
Citations
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Post COVID-19 cerebral venous sinus thrombosis; a case report.
Shwan A. Ahmad,Fahmi H. Kakamad,Hemin S. Mohamad,Bestoon Kh Salih,Shvan H. Mohammed,Berwn A. Abdulla,Abdulwahid M. Salih +6 more
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COVID-19 Vaccine-Induced Cerebral Sinus Thrombosis: Coincidence vs. Cause?
Abdalla N. Fadul,ELMustafa Abdalla,Elabbass Abdelmahmuod,Mohammed Abdulgayoom,Elrazi Ali,Akram Al-warqi,Hani Al-yahary +6 more
TL;DR: Two patients who suffered headaches and seizures after being vaccinated against COVID-19 were found to have CVST, which was treated with anticoagulation.
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Paraganglioma: An Unexpected Diagnosis in a Patient With Cerebral Venous Sinus Thrombosis and SARS-CoV-2 Infection
Olinda Miranda,Andre Maues Brabo Pereira,Margarida Castro,Nuno Carvalho,David Paiva,Ana Rita Costa,Clarisse Neves,Jorge Cotter +7 more
TL;DR: In this article, a 27-year-old male, with a recent SARS-CoV-2 infection, who went to the emergency department for a severe left occipital headache and was diagnosis with CVST.
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Neurological complications of COVID-19 in pediatric patients require comprehensive evaluation
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References
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COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up
Behnood Bikdeli,Mahesh V. Madhavan,David Jiménez,Taylor Chuich,Isaac Dreyfus,Elissa Driggin,Caroline Der Nigoghossian,Walter Ageno,Mohammad Madjid,Yutao Guo,Liang V. Tang,Yu Hu,Jay Giri,Mary Cushman,Isabelle Quéré,Evangelos Dimakakos,C. Michael Gibson,C. Michael Gibson,Giuseppe Lippi,Emmanuel J. Favaloro,Jawed Fareed,Joseph A. Caprini,Alfonso Tafur,John R. Burton,Dominic P. Francese,Elizabeth Y. Wang,Anna Falanga,Claire McLintock,Beverley J. Hunt,Alex C. Spyropoulos,Geoffrey D. Barnes,John W. Eikelboom,John W. Eikelboom,Ido Weinberg,Sam Schulman,Marc Carrier,Gregory Piazza,Gregory Piazza,Joshua A. Beckman,P. Gabriel Steg,Gregg W. Stone,Stephan Rosenkranz,Samuel Z. Goldhaber,Samuel Z. Goldhaber,Sahil A. Parikh,Manuel Monreal,Harlan M. Krumholz,Stavros Konstantinides,Jeffrey I. Weitz,Gregory Y.H. Lip,Gregory Y.H. Lip +50 more
TL;DR: The current understanding of the pathogenesis, epidemiology, management and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, and of those with preexistingThrombotic disease who develop CO VID-19 are reviewed.
Journal ArticleDOI
The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines.
Journal ArticleDOI
Cerebral Venous Sinus Thrombosis in COVID-19 Infection: A Case Series and Review of The Literature.
Katarina Dakay,Jared B. Cooper,Jessica Bloomfield,Philip Overby,Stephan A. Mayer,Rolla Nuoman,Ramandeep Sahni,Edwin Gulko,Gurmeen Kaur,Justin Santarelli,Chirag D. Gandhi,Fawaz Al-Mufti +11 more
TL;DR: The importance of maintaining a high index of suspicion for cVST in patients with COVID-19 infection, particularly those with unexplained cerebral hemorrhage, or infarcts with an atypical pattern for arterial occlusive disease, is illustrated.
Journal ArticleDOI
Cerebral venous sinus thrombosis associated with SARS-CoV-2; a multinational case series.
Ashkan Mowla,Banafsheh Shakibajahromi,Shima Shahjouei,Afshin Borhani-Haghighi,Nasrin Rahimian,Humain Baharvahdat,Soheil Naderi,Fariborz Khorvash,Davar Altafi,Seyed Amir Ebrahimzadeh,Ghasem Farahmand,Alaleh Vaghefi Far,Vijay Sharma,Saeideh Aghayari Sheikh Neshin,Georgios Tsivgoulis,Ramin Zand,Ramin Zand +16 more
TL;DR: It is suggested that compared to non-SARS-CoV-2 infected patients, CVST occurs in older patients, with lower rates of known CVST risk factors and might lead to a poorer outcome in the SARS- CoV- 2 infected group.
Journal ArticleDOI
Cerebral Venous Sinus Thrombosis in COVID-19 Patients: A Multicenter Study and Review of Literature.
Mohamad Abdalkader,Shamsh P. Shaikh,James E. Siegler,Anna M. Cervantes-Arslanian,Cristina Tiu,Razvan Alexandru Radu,Vlad Eugen Tiu,Dinesh V Jillella,Ossama Mansour,Víctor Vera,Ángel Chamorro,Jordi Blasco,Antonio M. López,Mudassir Farooqui,Lauren Thau,Ainsley Smith,Santiago Ortega Gutierrez,Thanh N. Nguyen,Tudor G. Jovin +18 more
TL;DR: In this paper, the authors reviewed all published cases of CVST in patients with COVID-19 infection from January 1, 2020 to November 13, 2020 and evaluated their clinical presentations, risk factors, clinical management, and outcome.