Journal ArticleDOI
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
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TLDR
The hypothesis that the compensatory acceleration of cerebral monoamine metabolism induced by antipsychotic drugs may be impaired in patients who develop extrapyramidal dysfunction is supported.About:
This article is published in Neuropharmacology.The article was published on 1970-05-01. It has received 81 citations till now. The article focuses on the topics: Extrapyramidal disorder & Monoamine neurotransmitter.read more
Citations
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The Dopamine Hypothesis of Schizophrenia: A Review*
Journal ArticleDOI
CSF monoamine metabolites in melancholia.
Marie Åsberg,Leif Bertilsson,Björn Mårtensson,Gianpaolo Scalia-Tomba,Peter Thorén,L. Träskman‐Bendz +5 more
TL;DR: It is suggested that the reduced concentrations of 5‐HIAA and HVA in the melancholic patients may be due to altered serotonin and/or dopamine functions in the central nervous system, which may be connected with an increased vulnerability to certain types of affective illness.
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Serum levels of anticholinergic drugs in treatment of acute extrapyramidal side effects.
Larry E. Tune,Joseph T. Coyle +1 more
TL;DR: There was a highly significant inverse correlation between the presence of acute extrapyramidal side effects due to neuroleptics and the serum levels of anticholinergics.
Journal ArticleDOI
Homovanillic Acid Measurement in Clinical Research: A Review of Methodology
TL;DR: Many factors must be considered in studies employing HVA as a possible index of central DA neuronal activity and the need for further methodological work is indicated to improve the use of body fluid HVA measurements in clinical research.
Journal ArticleDOI
Retarded depression and the dopamine metabolism.
H. M. van Praag,Jakob Korf +1 more
TL;DR: Findings suggest a decreased consumption of dopamine in the brain in retarded depression, which might be understood as an indication that, disorders of cerebral dopamine metabolism are related not so much to a specific nosological entity as to a given motor status, possibly that of hypokinesia.
References
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Journal ArticleDOI
Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain.
Arvid Carlsson,Margit Lindqvist +1 more
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[Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system].
H. Ehringer,Oleh Hornykiewicz +1 more
TL;DR: The distribution of noradrenaline and dopamine in human adult and newborn brains has been investigated in this paper, where the greatest amounts of dopamine were found in the hypothalamus, the central gray matter of the mesencephalon, the reticular formation and in the area postrema.
Journal ArticleDOI
A Survey of Drug-Induced Extrapyramidal Reactions
TL;DR: Drug-induced striopallidal symptoms can be adequately treated with antiparkinsonian drugs and a close parallel was found between drug-induced and naturally occurring extrapyramidal reactions.
Related Papers (5)
Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain.
Arvid Carlsson,Margit Lindqvist +1 more