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Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

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TLDR
The apparent increased consumption of LA, which was primarily from soybean oil, has likely decreased tissue concentrations of EPA and DHA during the 20th century.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2011-05-01 and is currently open access. It has received 742 citations till now. The article focuses on the topics: Unsaturated fatty acid & Eicosapentaenoic acid.

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Mechanisms of Action of (n-3) Fatty Acids

TL;DR: The very long-chain (n-3) PUFA have a range of physiological roles that relate to optimal cell membrane structure and optimal cell function and responses, and play a key role in preventing, and perhaps treating, many conditions of poor health and well-being.
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Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review.

TL;DR: Major sources, intake, and global consumption of n-3 and n-6 PUFAs are summarized and their metabolism to biosynthesize long-chain PUF as and eicosanoids and their roles in brain metabolism, cardiovascular disease, obesity, cancer, and bone health are discussed.
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Functional Roles of Fatty Acids and Their Effects on Human Health

TL;DR: It would seem more appropriate to describe biological effects and health impacts of individual named fatty acids, although it is recognized that this would be a challenge when communicating outside of an academic environment (eg, to consumers).
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Omega-6 fatty acids and inflammation.

TL;DR: The interaction of omega-3 and omega-6 fatty acids and their lipid mediators in the context of inflammation is complex and still not properly understood.
References
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Journal ArticleDOI

A simple method for the isolation and purification of total lipides from animal tissues.

TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
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Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol

TL;DR: The procedure developed is simple, rapid, and generally applicable t o lipids, and the results did not affect the validity of the method.
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Techniques for Testing the Constancy of Regression Relationships Over Time

TL;DR: In this paper, the stability over time of regression relationships is investigated using recursive residuals, defined to be uncorrelated with zero means and constant variance, and tests based on the cusum and cusume of squares of recursive residual coefficients are developed.
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Origins and evolution of the Western diet: health implications for the 21st century

TL;DR: The evolutionary collision of the authors' ancient genome with the nutritional qualities of recently introduced foods may underlie many of the chronic diseases of Western civilization.
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Essential fatty acids in health and chronic disease

TL;DR: Alpha-linolenic acid, found in green leafy vegetables, flaxseed, rapeseed, and walnuts, desaturates and elongates in the human body to EPA and DHA and by itself may have beneficial effects in health and in the control of chronic diseases.
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