Changes in thymic function with age and during the treatment of HIV infection
Citations
4,321 citations
Cites background from "Changes in thymic function with age..."
...cell receptor V repertoires [110], and evidence of residual thymic function in patients receiving HAART [111, 112] demonstrate that partial immune reconstitution occurs in these patients....
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1,563 citations
Cites background from "Changes in thymic function with age..."
...Formation of TRECs results from intrathymic TCR rearrangement (45)....
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1,526 citations
Cites background from "Changes in thymic function with age..."
...Naive T cells have high levels of T cell receptor (TCR) rearrangement excision circles (TRECs), which are diluted during clonal proliferatio...
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1,111 citations
950 citations
References
1,839 citations
"Changes in thymic function with age..." refers background in this paper
...Adult HIV-infected patients treated with highly active antiretroviral therapy (HAART) show a progressive increase in their number of naive CD4-positive T cell...
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1,309 citations
"Changes in thymic function with age..." refers methods in this paper
...We used this internal standard to quantify signal-joint TRECs in thymocytes and PBMCs by quantitative competitive (QC)-PC...
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1,090 citations
1,044 citations
735 citations
Additional excerpts
...Recent data indicate that the initial increase in CD4 p cells after HAART may result from release of sequestered cells from lymph node...
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