Journal ArticleDOI
Characterisation of human exposure pathways to perfluorinated compounds--comparing exposure estimates with biomarkers of exposure.
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In this paper, the relative importance of different exposure pathways of PFCs in a group of Norwegians and compare estimated intakes with internal doses obtained through biomonitoring was assessed.About:
This article is published in Environment International.The article was published on 2011-05-01. It has received 308 citations till now.read more
Citations
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Journal ArticleDOI
A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects
Elsie M. Sunderland,Xindi C. Hu,Clifton Dassuncao,Andrea K Tokranov,Charlotte C. Wagner,Joseph G. Allen +5 more
TL;DR: Understanding of sources and trends in human exposure to poly- and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer, immune function, metabolic outcomes, and neurodevelopment are reviewed.
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Behaviour and fate of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in drinking water treatment: a review
TL;DR: Early observations suggest that activated carbon adsorption, ion exchange, and high pressure membrane filtration may be effective in controlling these contaminants, however, branched isomers and the increasingly used shorter chain PFAS replacement products may be problematic as it pertains to the accurate assessment of PFAS behaviour through drinking water treatment processes.
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Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature☆☆☆
TL;DR: It is suggested that continued human exposure to even relatively low concentrations of PFOA in drinking water results in elevated body burdens that may increase the risk of health effects, and the human dose-response curve for several effects appears to be steepest at the lower exposure levels, including the general population range, with no apparent threshold for some endpoints.
Journal ArticleDOI
Perfluorinated Alkyl Acids in Blood Serum from Primiparous Women in Sweden: Serial Sampling during Pregnancy and Nursing, And Temporal Trends 1996-2010
Anders Glynn,Urs Berger,Anders Bignert,Shahid Ullah,Marie Aune,Sanna Lignell,Per Ola Darnerud +6 more
TL;DR: Temporal trends of blood serum levels of 13 perfluorinated alkyl acids (PFAAs) and perfLUorooctane sulfonamide (FOSA) in primiparous women from Uppsala County, Sweden, sampled 3 weeks after delivery 1996-2010 suggest one or several sources of exposure to the latter compounds have been reduced or eliminated, whereas Exposure to the former compounds has recently increased.
Journal ArticleDOI
Risk to human health related to the presence of perfluoroalkyl substances in food
Dieter Schrenk,Margherita Bignami,Laurent Bodin,James K. Chipman,Jesús del Mazo,Bettina Grasl-Kraupp,Christer Hogstrand,Laurentius Hoogenboom,Jean-Charles Leblanc,Carlo Nebbia,Elsa Nielsen,Evangelia E. Ntzani,Annette Petersen,Salomon Sand,Christiane Vleminckx,Heather M. Wallace,Lars Barregard,Sandra Ceccatelli,Jean-Pierre Cravedi,Thorhallur I. Halldorsson,Line Småstuen Haug,Niklas Johansson,Helle Katrine Knutsen,Martin Rose,Alain-Claude Roudot,Henk Van Loveren,Günter Vollmer,Karen Mackay,Francesca Riolo,Tanja Schwerdtle +29 more
TL;DR: The CONTAM Panel concluded that parts of the European population exceed this tolerable weekly intake (TWI) of 4.4 ng/kg bw per week, which is of concern, and protects against other potential adverse effects observed in humans.
References
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Journal ArticleDOI
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Christopher Lau,Katherine Anitole,Colette Hodes,David Y. Lai,Andrea Pfahles-Hutchens,Jennifer Seed +5 more
TL;DR: An overview of the recent advances in the toxicology and mode of action for PFAAs, and of the monitoring data now available for the environment, wildlife, and humans is provided.
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Sources, fate and transport of perfluorocarboxylates.
TL;DR: Transport pathways for PFCAs in the environment were reviewed, and it was concluded that, in addition to atmospheric transport/degradation of precursors, atmospheric and ocean water transport of the PFCA themselves could significantly contribute to their long-range transport.
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Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers.
Geary W. Olsen,Jean M. Burris,David J. Ehresman,John W. Froehlich,Andrew M. Seacat,John L. Butenhoff,Larry R. Zobel +6 more
TL;DR: Humans appear to have a long half-life of serum elimination of PFOS, PFHS, and PFOA, which may be due, in part, to a saturable renal resorption process.
Journal ArticleDOI
Biological Monitoring of Polyfluoroalkyl Substances: A Review
TL;DR: The pattern of contamination in wildlife varied among species and locations suggesting multiple emission sources and knowledge gaps with respect to the transport, accumulation, biodegradation, temporal/spatial trends and PFS precursors have been identified.