Chitosan—A versatile semi-synthetic polymer in biomedical applications
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Cites background from "Chitosan—A versatile semi-synthetic..."
...Chitosan can also be firstly modified by activated functional groups before inducing cross-linking by photo-induced reaction or enzymatic catalyzed reactions [38]....
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...Chitosan can indeed be either physically associated, coordinated with metal ions or irreversibly/chemically cross-linked into hydrogels [38]....
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...Chitosan is actually degraded in vivo by several proteases, and mainly lysozyme [9,38,39]....
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...Besides, some chemical modifications of chitosan structure could induce toxicity [38]....
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...The mechanical properties of hydrogels tend to mimic those of the soft body-tissues, which allows the gels to insure both functional and morphological characteristics of the tissue to be repaired [38]....
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"Chitosan—A versatile semi-synthetic..." refers background or methods in this paper
...[153]; this indicated that drug release from the microsphere matrix is diffusion controlled and obeys the Higuchi equation [148]....
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...at surface [148], but not from a sphere [149]....
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4,288 citations
"Chitosan—A versatile semi-synthetic..." refers background in this paper
...that are susceptible to enzymes or using polymers that are targeted by enzymes [212]....
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3,687 citations