Journal ArticleDOI
Chitosan-based hydrogels with injectable, self-healing and antibacterial properties for wound healing
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TLDR
The full-thickness skin defect model experiments showed that AC hydrogels could reduce inflammatory cell infiltration and accelerate wound healing significantly, and can shed new light on designing of the multifunctional dressings for wound healing.About:
This article is published in Carbohydrate Polymers.The article was published on 2022-01-15. It has received 48 citations till now. The article focuses on the topics: Self-healing hydrogels & Wound healing.read more
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Journal ArticleDOI
Recent Advances of Chitosan Formulations in Biomedical Applications
Mohammed A.S. Abourehab,Sheersha Pramanik,Mohamed A. Abdelgawad,Bassam M Abualsoud,Ammar Kadi,Mohammad Javed Ansari,Amar Deepak +6 more
TL;DR: Chitosan, a naturally abundant cationic polymer, is chemically composed of cellulose-based biopolymers derived by deacetylating chitin and offers several attractive characteristics such as renewability, hydrophilicity, biodegradability, biocompatibility, non-toxicity, and a broad spectrum of antimicrobial activity towards gram-positive and gram-negative bacteria as well as fungi as mentioned in this paper .
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Injectable oxidized alginate/carboxylmethyl chitosan hydrogels functionalized with nanoparticles for wound repair.
Lei Ma,Yunfei Tan,Xiangyu Chen,Yaqin Ran,Qiulan Tong,Liwen Tang,Wen Su,Xiaoliang Wang,Xudong Li +8 more
TL;DR: Wang et al. as mentioned in this paper used nanosized-EGCG covered with Ag nanoparticles (AE NPs) with radicals scavenging capability to functionalize injectable oxidized alginate/carboxylmethyl chitosan hydrogel.
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Diversified antibacterial modification and latest applications of polysaccharide-based hydrogels for wound healthcare
TL;DR: In this paper , the current antibacterial modes and mechanisms, as well as the antibacterial modification methods of natural polysaccharides hydrogels were reviewed, and the latest advances of antibacterial hydrogel of polysccharides (chitosan, alginate, cellulose, starch, and hyaluronic acid) as protective shields was discussed.
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Bacterial cellulose reinforced chitosan-based hydrogel with highly efficient self-healing and enhanced antibacterial activity for wound healing.
TL;DR: In this paper , a bio-based hydrogel with multifunctional properties is designed based on quaternized chitosan and dialdehyde bacterial cellulose for wound dressing.
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Preparation of chitosan-cellulose-benzyl isothiocyanate nanocomposite film for food packaging applications.
TL;DR: In this article , a double-layer nanocomposite film was prepared to improve the mechanical and barrier properties of cellulose and chitosan (CS) and to allow the application of volatile antibacterial benzyl isothiocyanate (BITC) in active packaging.
References
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Journal ArticleDOI
Chitosan chemistry and pharmaceutical perspectives.
TL;DR: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. S. Nagar, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of medicine, Jerusalem 91120, Israel.
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Molecular regulation of vessel maturation.
TL;DR: The maturation of nascent vasculature, formed by vasculogenesis or angiogenesis, requires recruitment of mural cells, generation of an extracellular matrix and specialization of the vessel wall for structural support and regulation of vessel function.
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
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Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
TL;DR: In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.
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Physical Double-Network Hydrogel Adhesives with Rapid Shape Adaptability, Fast Self-Healing, Antioxidant and NIR/pH Stimulus-Responsiveness for Multidrug-Resistant Bacterial Infection and Removable Wound Dressing
TL;DR: In vivo experiments prove that the hydrogels have good hemostasis of skin trauma and high killing ratio for methicillin‐resistant staphylococcus aureus and achieve better wound closure and healing of skin incision than medical glue and surgical suture.