Chronic Obstructive Pulmonary Disease in the Elderly

doi:10.4172/2167-7182.1000E140

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Chronic Obstructive Pulmonary Disease in the Elderly

Journal Article•DOI•

Chronic Obstructive Pulmonary Disease in the Elderly

Essam A El-Moselhy, Abdel Hay I Abdel Hay

05 May 2016-Journal of gerontology and geriatric research (OMICS International)-Vol. 5, Iss: 6, pp 1-1

TL;DR: Elderly is robustly accompanied with raise prevalence of chronic obstructive pulmonary disease (COPD) and prevalence of COPD in subjects aged 65 years and more is estimated at 14.2% in contrast with 9.9% in those aged 40 years or more.

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Abstract: Elderly is robustly accompanied with raise prevalence of chronic obstructive pulmonary disease (COPD). Prevalence of COPD in subjects aged 65 years and more is estimated at 14.2% (11.0%-18.0%) in contrast with 9.9% (8.2% to 11.8%) in those aged 40 years or more.

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Journal Article•DOI•

"Celebrating old age": an obsolete expression during the COVID-19 pandemic? Medical, social, psychological, and religious consequences of home isolation and loneliness among the elderly

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Alexandru Burlacu, Ionut Mavrichi¹, Radu Crisan-Dabija, Daniel Jugrin¹, Smaranda Buju, Bogdan Artene, Adrian Covic - Show less +3 more•Institutions (1)

University of Bucharest¹

02 Mar 2021-Archives of Medical Science

TL;DR: Higher levels of mortality/morbidity due to “CO VID-19 versus non-COVID-19” polarisation oblige the healthcare community to find ways to provide proper care for its elders, and various religious practices provide resources for coping with isolation/overcoming loneliness.

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Abstract: Since epidemiological arguments favouring self-isolation during the COVID-19 pandemic are widely recommended, the consequences of social isolation/loneliness of older people considered to be at higher risk for severe illness are neglected. We identified and described medical, social, psychological, and religious issues, indirectly generated by the COVID-19 lockdown. Mortality induced by SARS-CoV-2 and death from other "neglected" issues were put in balance. Arguments for strict lockdown from most European countries are compared with a relaxed approach, as has been applied in Sweden. Social isolation affects disproportionally the elderly, transforming it into a public health concern. One witnesses openly ageist discourse, while painful decisions to prioritising ventilation for younger patients deepens the sense of hopelessness. Fear has led to anxiety disorders and depression. Various religious practices provide resources for coping with isolation/overcoming loneliness. Higher levels of mortality/morbidity due to "COVID-19 versus non-COVID-19" polarisation oblige the healthcare community to find ways to provide proper care for its elders.

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24 citations

Journal Article•DOI•

Un ejemplo de cooperación para la implementación de programas relacionados con el desarrollo de ejercicio en ancianos frágiles: programa europeo Erasmus + «Vivifrail»

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Mikel Izquierdo¹, Alvaro Casas-Herrero, Nicolás Martínez-Velilla, Cristina Alonso-Bouzon, Leocadio Rodríguez-Mañas - Show less +1 more•Institutions (1)

Universidad Pública de Navarra¹

01 Mar 2017-Revista Española de Geriatría y Gerontología

13 citations

Journal Article•DOI•

Sarcopenia en ancianos con antecedente de EPOC/asma : resultados del estudio SABE - Bogotá

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Miguel Germán Borda¹, Carlos Andrés Celis-Preciado, Mario Ulises Pérez-Zepeda, Julián David Ríos-Zuluaga¹, Carlos Cano-Gutierrez¹ - Show less +1 more•Institutions (1)

Pontifical Xavierian University¹

01 Nov 2017-Revista Española de Geriatría y Gerontología

TL;DR: La conveniencia de descartar sarcopenia en pacientes con EPOC/asma para plantear intervenciones como soporte nutricional y programas of ejercicio, idealmente en el marco of programas de rehabilitacion pulmonar.

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12 citations

Journal Article•DOI•

Acupuncture techniques for COPD: a systematic review

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Carles Fernández-Jané¹, Jordi Vilaró¹, Yutong Fei², Congcong Wang², Jianping Liu², Na Huang², Ruyu Xia², Xia Tian², Rui-Xue Hu², Lingzi Wen², Mingkun Yu², Natàlia Gómara-Toldrà³, Natàlia Gómara-Toldrà¹, Mireia Solà-Madurell, Mercè Sitjà-Rabert¹ - Show less +11 more•Institutions (3)

Ramon Llull University¹, Beijing University of Chinese Medicine², University of Vic³

06 May 2020

TL;DR: Overall, strong evidence in favour of any technique was not found, but acupressure could be beneficial for dyspnoea, quality of life and anxiety, but this is based on low quality trials.

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Abstract: This is the second part of a large spectrum systematic review which aims to identify and assess the evidence for the efficacy of non-pharmacological acupuncture techniques in the treatment of chronic obstructive pulmonary disease (COPD). The results of all techniques except for filiform needle are described in this publication. Eleven different databases were screened for randomised controlled trials up to June 2019. Authors in pairs extracted the data and assessed the risk of bias independently. RevMan 5.3 software was used for the meta-analysis. Thirty-three trials met the inclusion criteria, which involved the follow techniques: AcuTENS (7 trials), moxibustion (11 trials), acupressure (7 trials), ear acupuncture (6 trials), acupressure and ear acupuncture combined (1 trial) and cupping (1 trial). Due to the great heterogeneity, only 7 meta-analysis could be performed (AcuTENS vs sham on quality of life and exercise capacity, acupressure vs no acupressure on quality of life and anxiety and ear acupuncture vs sham on FEV1 and FEV1/FVC) with only acupressure showing statistical differences for quality of life (SMD: -0.63 95%CI: − 0.88, − 0.39 I2 = 0%) and anxiety (HAM-A scale MD:-4.83 95%CI: − 5.71, − 3.94 I2 = 0%). Overall, strong evidence in favour of any technique was not found. Acupressure could be beneficial for dyspnoea, quality of life and anxiety, but this is based on low quality trials. Further large well-designed randomised control trials are needed to elucidate the possible role of acupuncture techniques in the treatment of COPD. PROSPERO (identifier: CRD42014015074 ).

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11 citations

Cites background or methods from "Chronic Obstructive Pulmonary Disea..."

...Moxibustion The thirteen studies included used multiple moxibustion techniques, including moxa stick [16, 18, 20, 22, 23, 26], heat sensitivity moxibustion [23, 24, 27], cone moxibustion [8, 17], moxibustion boxes [25] and ginger moxibustion [19, 21]....
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...Treatment regimens were also different, with two studies using from 3 to 6 treatment courses of 10–14 consecutive days during a year [16, 18], three studies using daily treatments for a period of 2 to 4 weeks [19, 20, 23], two using from 2 to 5 treatments a week over a month [8, 21], two trials using 5 treatments a week over 3 to 4 months [24, 25], one using nine treatments every 10 days over 3 months [17] and one trial using one treatment per month [22]....
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...Table 2 Detailed risk of bias of each trial Random sequence generation Allocation concealment Blinding of participants Blinding of outcome assessment Incomplete outcome data Selective outcome reporting Other sources of bias AcuTENS Lau, 2008 [9] Low Low Low Low Low Unclear Low Liu X, 2015 [10] Low Low Low Low Low Unclear Low Ngai, 2010 [11] Low Unclear Low Low Low Unclear Low Jones, 2011 [12] Low Unclear Low Low Unclear High Unclear Öncü, 2017 [13] Low Unclear Low Unclear Unclear Unclear Unclear Shou, 2014 [14] Low Unclear Unclear Unclear Low Unclear Unclear Wen Q 2011 [15] Low Unclear Low Unclear Low Unclear Unclear Moxibustion Bai 2018 [26] Unclear Unclear High Unclear Unclear Unclear Unclear Cheng AP, 2011 [23] Unclear Unclear Unclear Unclear Unclear Low Unclear Cui XX, 2015 [22] Low Unclear Unclear Unclear Unclear Low Unclear Guang, 2017 [25] Low Unclear High Unclear Unclear Unclear Unclear He F, 2013 [21] Unclear Unclear High High Unclear Low Low Liang, 2018 [27] Low Unclear High Unclear Unclear Unclear Unclear Liu SR, 2015 [20] Low Unclear Unclear Unclear Unclear Low Unclear Tang J 2012 [19] Unclear Unclear Unclear Unclear Unclear Low Unclear Wang WH, 2016 [18] Unclear Unclear Unclear Unclear Low Unclear Unclear Wen X, 2013 [8] Low Unclear Unclear Unclear Unclear Low Unclear Yang XQ, 2016 [17] Low Unclear Unclear Unclear Unclear Low Unclear Zhang QY, 2016 [16] Low Unclear Unclear Unclear Unclear Low Unclear Zhe, 2017 [24] Low Unclear High Unclear Unclear Unclear Unclear Acupressure Guo 2017 [32] Low Unclear High Unclear Unclear Unclear Unclear Huang 2018 [33] Low Unclear High Unclear Unclear Unclear Unclear Maa, 1997 [30] Low Unclear Low Unclear Low Unclear Low Tsay, 2005 [28] Unclear Unclear Low Low Low Unclear Unclear Wu, 2004 [31], 2007 [29] Unclear Unclear Unclear Unclear Unclear Unclear Unclear Wu, 2017 [34] Low Unclear High Unclear Unclear Unclear Unclear Xu 2018 [35] Unclear Unclear High Unclear Unclear Unclear Unclear Ear acupuncture Cao L, 2012 [36] Low Low Low Low Low Unclear Unclear Hu ZH, 1997 [41] Unclear Unclear Unclear Unclear Low Unclear Unclear Jin RF, 2009 [37] Unclear Unclear Unclear Unclear Low Low Unclear Li, 2017 [40] Unclear Unclear High Unclear Low Unclear Unclear Pang CL, 2014 [39] Unclear Unclear Unclear Unclear Low Unclear Unclear Pang CL, 2016 [38] Unclear Unclear High Unclear Low Low Unclear Acupressure plus ear acupuncture Rao, 2017 [42] Low Unclear High Unclear Unclear Unclear Unclear Cupping Xiao W, 2009 [43] Unclear Unclear High Unclear Low Unclear Unclear Fernández-Jané et al....
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Journal Article•DOI•

Prescripción potencialmente inadecuada en pacientes mayores grandes polimedicados según criterios «STOPP»

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L. Terán-Álvarez, M.J. González-García, A.L. Rivero-Pérez, J.C. Alonso-Lorenzo, J.A. Tarrazo-Suárez - Show less +1 more

01 Jan 2016-Semergen - Medicina De Familia

TL;DR: Analizar la prescripcion potencialmente inadecuada (PPI) en pacientes ancianos grandes polimedicados segun criterios del Screening Tool of Older Person's Prescriptions (STOPP).

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Abstract: Resumen Introduccion La adecuacion en la prescripcion terapeutica es especialmente relevante en pacientes mayores. El objetivo de este trabajo es analizar la prescripcion potencialmente inadecuada (PPI) en pacientes ancianos grandes polimedicados segun criterios del Screening Tool of Older Person's Prescriptions (STOPP). Pacientes y metodos Estudio descriptivo transversal realizado en el centro de salud Siero-Sariego (Asturias), en el que participaron todos los pacientes mayores de 64 anos adscritos al centro, grandes polimedicados (consumo ≥10 farmacos durante 6 meses). Se revisaron los 65 criterios del Screening Tool of Older Person's Prescriptions en la historia clinica electronica de atencion primaria. Se recogieron variables sociodemograficas, farmacos prescritos y patologias cronicas. Se calculo el indice de Charlson. Se realizaron distribuciones de frecuencias de cada criterio y se exploraron causas relacionadas con la PPI a traves de tablas de contingencia, correlacion de Spearman y regresion lineal. Resultados Trescientos cuarenta y nueve grandes polimedicados (prevalencia: 6,4 [IC 95% : 5,76-7,08]), media: 79 anos (DE : 3,7), 62,2% mujeres, 14% institucionalizados. Media de farmacos: 11,5 (DE : 1,7). Patologias mas frecuentes: hipertension arterial (64%), diabetes (46%) y patologia osteoarticular (41%). El 72,9% de los polimedicados tenia al menos una PPI. Media: 1,32 (DE : 1,2). Criterios del Screening Tool of Older Person's Prescriptions mas incumplidos: duplicidad terapeutica (25,2%), uso de benzodiacepinas de vida media larga (15,8%) y uso inadecuado de aspirina (10,9%). Se encontro asociacion entre presentar alguna PPI y el numero de farmacos dispensados (OR = 1,22 [IC 95% : 1,04-1,43]) y de forma inversa al indice de Charlson (OR = 0,76 [IC 95% : 0,65-0,89]). Conclusiones La PPI es frecuente en grandes polimedicados. Debe prestarse especial atencion al uso de farmacos psicotropos, implicados en un volumen importante de PPI.

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10 citations

References

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Journal Article•DOI•

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

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Jørgen Vestbo¹, Suzanne S. Hurd, Alvar Agusti², Paul W. Jones³, Claus Vogelmeier⁴, Antonio Anzueto⁵, Peter J. Barnes⁶, Leonardo M. Fabbri⁷, Fernando J. Martinez⁸, Masaharu Nishimura⁹, Robert A. Stockley, Don D. Sin¹⁰, Roberto Rodriguez-Roisin² - Show less +9 more•Institutions (10)

University of Manchester¹, University of Barcelona², St George's Hospital³, University of Marburg⁴, University of Texas Health Science Center at San Antonio⁵, Imperial College London⁶, University of Modena and Reggio Emilia⁷, University of Michigan⁸, Hokkaido University⁹, University of British Columbia¹⁰

15 Sep 2007-American Journal of Respiratory and Critical Care Medicine

TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.

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Abstract: Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease worldwide, according to a study published by the World Bank/World Health Organization. Yet, COPD remains relatively unknown or ignored by the public as well as public health and government officials. In 1998, in an effort to bring more attention to COPD, its management, and its prevention, a committed group of scientists encouraged the U.S. National Heart, Lung, and Blood Institute and the World Health Organization to form the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Among the important objectives of GOLD are to increase awareness of COPD and to help the millions of people who suffer from this disease and die prematurely of it or its complications. The first step in the GOLD program was to prepare a consensus report, Global Strategy for the Diagnosis, Management, and Prevention of COPD, published in 2001. The present, newly revised document follows the same format as the original consensus report, but has been updated to reflect the many publications on COPD that have appeared. GOLD national leaders, a network of international experts, have initiated investigations of the causes and prevalence of COPD in their countries, and developed innovative approaches for the dissemination and implementation of COPD management guidelines. We appreciate the enormous amount of work the GOLD national leaders have done on behalf of their patients with COPD. Despite the achievements in the 5 years since the GOLD report was originally published, considerable additional work is ahead of us if we are to control this major public health problem. The GOLD initiative will continue to bring COPD to the attention of governments, public health officials, health care workers, and the general public, but a concerted effort by all involved in health care will be necessary.

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17,023 citations

"Chronic Obstructive Pulmonary Disea..." refers background in this paper

...The major COPD management fundaments are to evaluate and observe disease severity, minimize risk factors, prevent and manage symptoms, promote health, and raise capability to exercise [5]....
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Global Initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease

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C Lenfant, N Khaltaev

01 Jan 2006

2,707 citations

Journal Article•DOI•

Systemic manifestations and comorbidities of COPD

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Peter J. Barnes¹, Bartolome R. Celli•Institutions (1)

National Institutes of Health¹

01 May 2009-European Respiratory Journal

TL;DR: Treatment of COPD inflammation may concomitantly treat systemic inflammation and associated comorbidities, however, new broad-spectrum anti-inflammatory treatments, such as phosphodiesterase 4 inhibitors, have significant side-effects so it may be necessary to develop inhaled drugs in the future.

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Abstract: Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a complex disease involving more than airflow obstruction. Airflow obstruction has profound effects on cardiac function and gas exchange with systemic consequences. In addition, as COPD results from inflammation and/or alterations in repair mechanisms, the "spill-over" of inflammatory mediators into the circulation may result in important systemic manifestations of the disease, such as skeletal muscle wasting and cachexia. Systemic inflammation may also initiate or worsen comorbid diseases, such as ischaemic heart disease, heart failure, osteoporosis, normocytic anaemia, lung cancer, depression and diabetes. Comorbid diseases potentiate the morbidity of COPD, leading to increased hospitalisations, mortality and healthcare costs. Comorbidities complicate the management of COPD and need to be evaluated carefully. Current therapies for comorbid diseases, such as statins and peroxisome proliferator-activated receptor-agonists, may provide unexpected benefits for COPD patients. Treatment of COPD inflammation may concomitantly treat systemic inflammation and associated comorbidities. However, new broad-spectrum anti-inflammatory treatments, such as phosphodiesterase 4 inhibitors, have significant side-effects so it may be necessary to develop inhaled drugs in the future. Another approach is the reversal of corticosteroid resistance, for example with effective antioxidants. More research is needed on COPD comorbidities and their treatment.

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1,518 citations

"Chronic Obstructive Pulmonary Disea..." refers background in this paper

...Systemic inflammation may set or get worsen the co-morbid illnesses, as ischemic heart disease, heart failure, anaemia, diabetes mellitus, depression, osteoporosis, and lung cancer [3]....
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Journal Article•DOI•

Global burden of COPD: systematic review and meta-analysis

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Ronald J. Halbert, J.L. Natoli¹, J.L. Natoli², Anacleto Gano¹, E. Badamgarav¹, A. S. Buist, David M. Mannino³ - Show less +3 more•Institutions (3)

Cerner¹, University of California, Los Angeles², University of Kentucky³

01 Sep 2006-European Respiratory Journal

TL;DR: The aim of this study was to quantify the global prevalence of chronic obstructive pulmonary disease by means of a systematic review and random effects meta-analysis and population-based prevalence estimates published during the period 1990–2004.

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Abstract: The aim of this study was to quantify the global prevalence of chronic obstructive pulmonary disease (COPD) by means of a systematic review and random effects meta-analysis. PubMed was searched for population-based prevalence estimates published during the period 1990-2004. Articles were included if they: 1) provided total population or sex-specific estimates for COPD, chronic bronchitis and/or emphysema; and 2) gave method details sufficiently clearly to establish the sampling strategy, approach to diagnosis and diagnostic criteria. Of 67 accepted articles, 62 unique entries yielded 101 overall prevalence estimates from 28 different counties. The pooled prevalence of COPD was 7.6% from 37 studies, of chronic bronchitis alone (38 studies) was 6.4% and of emphysema alone (eight studies) was 1.8%. The pooled prevalence from 26 spirometric estimates was 8.9%. The most common spirometric definitions used were those of the Global Initiative for Chronic Obstructive Lung Disease (13 estimates). There was significant heterogeneity, which was incompletely explained by subgroup analysis (e.g. age and smoking status). The prevalence of physiologically defined chronic obstructive pulmonary disease in adults aged > or =40 yrs is approximately 9-10%. There are important regional gaps, and methodological differences hinder interpretation of the available data. The efforts of the Global Initiative for Chronic Obstructive Lung Disease and similar groups should help to standardise chronic obstructive pulmonary disease prevalence measurement.

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1,416 citations

"Chronic Obstructive Pulmonary Disea..." refers background in this paper

...8%) in those aged 40 years or more [1]....
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Journal Article•DOI•

Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion

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Jean-Paul Janssens¹•Institutions (1)

Geneva College¹

01 Sep 2005-Clinics in Chest Medicine

TL;DR: The respiratory system remains capable of maintaining adequate gas exchange at rest and during exertion during the entire lifespan, with only a slight decrease in Pa(O2) and no significant change inPa(CO2).

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201 citations

"Chronic Obstructive Pulmonary Disea..." refers background in this paper

...Regardless of these changes, the respiratory system still remains eligible to preserving appropriate gas exchange at rest and in state of effort during the whole lifespan, with only a minor reduce in Pa(O2) and no considerable change in Pa(CO2) [2]....
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