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Journal ArticleDOI

Cirrhopetalanthrin, a dimeric phenanthrene derivative from the orchid Cirrhopetalum maculosum

01 Jan 1990-Phytochemistry (Pergamon)-Vol. 29, Iss: 1, pp 271-274
TL;DR: Cirrhopetalanthrin, a new dimeric phenanthrene derivative, was isolated from the orchid maculosum and its structure was deduced from spectral and chemical evidence as discussed by the authors.
About: This article is published in Phytochemistry.The article was published on 1990-01-01. It has received 33 citations till now.
Citations
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Journal ArticleDOI
TL;DR: The present study furnishes an overview of the hydroxy or/and methoxy-substituted 9,10-dihydro/phenanthrene, methylated, prenylated and other monomeric derivatives, dimeric and trimeric phenanthrenes and their biological activities.

282 citations

Journal ArticleDOI
TL;DR: Compounds 1-3 and denthyrsinin (1,5,7-trimethoxyphenanthrene-2,6-diol; 4) showed significant cytotoxic activities against Hela (13.5, 9.5 and 4.8 microM, respectively) cell lines.

79 citations


Cites background from "Cirrhopetalanthrin, a dimeric phena..."

  • ...A fairly large number of phenanthrenes and 9,10dihydrophenanthrenes were reported from a series of orchids, e.g., Dendrobium (Lee et al., 1995), Bulbophyllum (Majumder et al., 1999), Eria (Bhandari et al., 1985), Lusia (Majumder and Lahiri, 1990), Maxillaria (Estrada et al., 1999) et al. Four symmetric dimeric phenanthrenes were reported early from Orchid Cirrhopetalum maculosum ( Majumder et al., 1990 ), Bulbophyllum reptans (Majumder et ......

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Book ChapterDOI
01 Jan 2016
TL;DR: Orchid phytochemicals that have been studied include alkaloids, bibenzyls, phenanthrenes, stilbenoids, phenols, flavonoids, anthocyanins and polysaccharides, which exhibit antioxidant, anti-inflammatory, antimicrobial, antihelminthic, anticoagulant, antidiabetic and lipid-lowering properties.
Abstract: Orchid phytochemicals that have been studied include alkaloids, bibenzyls, phenanthrenes, stilbenoids, phenols, flavonoids, anthocyanins and polysaccharides. Many of these compounds exhibit antioxidant, anti-inflammatory, antimicrobial, antihelminthic, anticoagulant, antidiabetic and lipid-lowering properties. Some compounds are cytotoxic, prevent angiogenesis and tumour spread and promote programmed cell death of cancer cells. Some compounds protect nerve cells against chemicals and oxygen deprivation (stroke), promote nerve cell regeneration, protect the skin from ultraviolet damage, protect the liver against poisons such as carbon tetrachloride, prevent calcium loss from bone and enhance foetal lung maturation. This chapter provides a short account of the characteristics of the various groups of compounds, including their properties.

54 citations


Cites background from "Cirrhopetalanthrin, a dimeric phena..."

  • ...…1989, 2000; Bai et al. 1991), B. formosana (Lin et al. 2005), Bulbophyllum reptens (Majumder et al. 1999), B. maculosum (Cirrhopetalum maculosum) (Majumder et al. 1990) B. vaginatum (Leong and Harrison 2004), Cremastra appendiculata (Xue et al. 2005), Dendrobium plicatile (Honda and Yamaki…...

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Journal ArticleDOI
TL;DR: Antifibrotic activity of compounds 1- 19 was evaluated employing HSC-T6, an immortalized rat hepatic stellate cell line, as an in vitro assay system by assessing cell proliferation.
Abstract: Two new phenanthrenes (1 and 6) and four new dihydrophenanthrenes (2–5) were isolated from a methanolic extract of Dendrobium nobile stems, along with 13 known phenanthrenes and dihydrophenanthrenes (7–19). By spectroscopic analysis, the structures of compounds 1–6 were determined as 2,8-dihydroxy-3,4,7-trimethoxyphenanthrene (1), 3-hydroxy-2,4,7-trimethoxy-9,10-dihydrophenanthrene (2), 2,8-dihydroxy-3,4,7-trimethoxy-9,10-dihydrophenanthrene (3), 2-hydroxy-4,7-dimethoxy-9,10-dihydrophenanthrene (4), 2,2′-dihydroxy-3,3′,4,4′,7,7′-hexamethoxy-9,9′,10,10′-tetrahydro-1,1′-biphenanthrene (5), and 2,3,5-trihydroxy-4,9-dimethoxyphenanthrene (6), respectively. Antifibrotic activity of compounds 1–19 was evaluated employing HSC-T6, an immortalized rat hepatic stellate cell line, as an in vitro assay system by assessing cell proliferation.

53 citations

References
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Journal ArticleDOI
TL;DR: Moscatilin, a new bibenzyl derivative isolated from the orchid Dendrobium moscatum, was shown to have the structure 4,4′-dihydroxy-3,3′,5-trimethoxybibensyl.

81 citations

Journal ArticleDOI
TL;DR: 2,7-Dihydroxy-4-methoxy-9,10-dihydrophenanthrene was isolated and identified from the whole plant of Coelogyne ochracea and C. elata.

77 citations

Journal ArticleDOI
TL;DR: An amorphous phenanthrene, named nudol has been isolated from Eulophia nuda, Eria carinata and E. stricta and was identified as 2,7-dihydroxy-3,4-dimethoxyphenanthrene.

74 citations

Journal ArticleDOI
TL;DR: Flavanthrin, the first dimeric 9,10-dihydrophenanthrene derivative, was isolated from the orchid Eria flava which also yielded the previously reported 9, 10-dibhrenanthrene coelonin this paper.

54 citations