Journal ArticleDOI
Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled trial
Ebrahim Kouchaki,Omid Reza Tamtaji,Mahmoud Salami,Fereshteh Bahmani,Reza Daneshvar Kakhaki,Elmira Akbari,Maryam Tajabadi-Ebrahimi,Parvaneh Jafari,Zatollah Asemi +8 more
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TLDR
It is demonstrated that the use of probiotic capsule for 12 weeks among subjects with MS had favorable effects on EDSS, parameters of mental health, inflammatory factors, markers of insulin resistance, HDL-, total-/HDL-cholesterol and MDA levels.About:
This article is published in Clinical Nutrition.The article was published on 2017-10-01. It has received 199 citations till now. The article focuses on the topics: Placebo-controlled study & Placebo.read more
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The Microbiota-Gut-Brain Axis
John F. Cryan,Kenneth J. O’Riordan,Caitlin S. M. Cowan,Kiran V. Sandhu,Thomaz F.S. Bastiaanssen,Marcus Boehme,Martín Gabriel Codagnone,Sofia Cussotto,Christine Fülling,Anna V. Golubeva,Katherine E. Guzzetta,Minal Jaggar,Caitriona M. Long-Smith,Joshua M. Lyte,Jason A. Martin,Alicia Molinero-Perez,Gerard M. Moloney,Emanuela Morelli,Enrique Morillas,Rory C. O'Connor,Joana S Cruz-Pereira,Veronica L. Peterson,Kieran Rea,Nathaniel L. Ritz,Eoin Sherwin,Simon Spichak,Emily M. Teichman,Marcel van de Wouw,Ana Paula Ventura-Silva,Shauna E. Wallace-Fitzsimons,Niall P. Hyland,Gerard Clarke,Timothy G. Dinan +32 more
TL;DR: Future studies will focus on understanding the mechanisms underlying the microbiota-gut-brain axis and attempt to elucidate microbial-based intervention and therapeutic strategies for neuropsychiatric disorders.
Journal ArticleDOI
The microbiome, cancer, and cancer therapy.
Beth A. Helmink,M.A. Wadud Khan,Amanda Hermann,Vancheswaran Gopalakrishnan,Jennifer A. Wargo +4 more
TL;DR: The microbiome influences response to cancer therapy, including cancer immunotherapy, and also plays a role in therapeutic toxicity.
Journal ArticleDOI
Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial.
Elmira Akbari,Zatollah Asemi,Reza Daneshvar Kakhaki,Fereshteh Bahmani,Ebrahim Kouchaki,Omid Reza Tamtaji,Gholam Ali Hamidi,Mahmoud Salami +7 more
TL;DR: It is demonstrated that probiotic consumption for 12 weeks positively affects cognitive function and some metabolic statuses in the AD patients and no considerable effect on other biomarkers of oxidative stress and inflammation, fasting plasma glucose, and other lipid profiles.
Journal ArticleDOI
The gut microbiome in neurological disorders.
TL;DR: Research into the role of the gut microbiome in modulating brain function has rapidly increased over the past 10 years, albeit chiefly in animal models, and interpretation of such data is often difficult given that the composition of the microbiome is influenced by various factors such as diet and exercise.
Journal ArticleDOI
Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier.
Lesley Hoyles,Tom Snelling,Umm-Kulthum Umlai,Jeremy K. Nicholson,Simon R. Carding,Simon R. Carding,Robert C. Glen,Robert C. Glen,Simon McArthur +8 more
TL;DR: Interactions between circulating gut-derived microbial metabolites, and the blood–brain barrier (BBB) also contribute to the gut-brain axis, representing a fourth facet of the gut–brain axis that warrants further attention.
References
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An inventory for measuring depression
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The positive and negative affect schedule (PANAS): construct validity, measurement properties and normative data in a large non-clinical sample.
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