Clinical burden of relapses in aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder: A single center cohort analysis.
Robert Kadish,Stacey L. Clardy,Minying Royston,Imran Tanvir,Tavan Parker,Joseph Biskupiak,Adrian Kielhorn +6 more
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In this paper, a retrospective, observational analysis of 47 patients with aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder (AQP4-IgG+ NMOSD) enrolled at the University of Utah healthcare system was conducted.About:
This article is published in Journal of Neuroimmunology.The article was published on 2022-01-15 and is currently open access. It has received 2 citations till now. The article focuses on the topics: Neuromyelitis optica & Medicine.read more
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Pain in neuromyelitis optic spectrum disorder.
TL;DR: In this paper , the authors retrospectively reviewed the medical records of 145 patients with neuromyelitis optica spectrum disorder (NMOSD) admitted to a hospital between July 2016 and June 2019, revealing that the incidence of pain in NMOSD is high and can be used for disease localization.
Journal ArticleDOI
Clinical and epidemiological correlates of treatment change in patients with NMOSD: insights from the CIRCLES cohort
Shervin Gholizadeh,A. Exuzides,K. Lewis,C. Palmer,Michael Waltz,John Rose,Anna Marie Jolley,Jacinta M. Behne,Megan K Behne,Terrence F. Blaschke,Terry J. Smith,Jennifer A. Sinnott,Lawrence J. Cook,Michael R. Yeaman,Ines M Aguerre,Lilyana Amezcua,Tanuja Chitnis,Jessica C. Lewis,Casey E. Engel,May H. Han,Eric C. Klawiter,Alexandra S Kocsik,Mason Kruse-Hoyer,Libby Levine,Michael J. Levy,Melanie Marcille,Maureen A. Mealy,Stephanie Moore,Devin S. Mullin,Katherine E. Nelson,Kaho B. Onomichi,Sarah M. Planchon,A. Pruitt,Pavle Repovic,Claire S Riley,Zoe Rimler,Andrew W. Russo,Collin Tanchanco Ocampo,Anna Tomczak +38 more
TL;DR: In this article , the authors used real-world data to identify clinical and epidemiological correlates of treatment change in patients with Neuromyelitis optica spectrum disorders (NMOSD).
References
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Journal ArticleDOI
Rating neurologic impairment in multiple sclerosis An expanded disability status scale (EDSS)
TL;DR: A new Expanded Disability Status Scale (EDSS) is presented, with each of the former steps (1,2,3 … 9) now divided into two (1.0, 1.5, 2.0 … 9).
Journal ArticleDOI
The clinical course of neuromyelitis optica (Devic's syndrome)
TL;DR: Clinical, laboratory, and imaging features generally distinguish neuromyelitis optica from MS, and patients with relapsing optic neuritis and myelitis may have neuromyeliitis opticas rather than MS.
Journal ArticleDOI
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Sven Jarius,Klemens Ruprecht,Brigitte Wildemann,Tania Kuempfel,Marius Ringelstein,Christian Geis,Ingo Kleiter,Ingo Kleiter,Christoph Kleinschnitz,Achim Berthele,Johannes Brettschneider,Kerstin Hellwig,Bernhard Hemmer,Ralf A. Linker,Ralf A. Linker,Florian Lauda,Christoph Mayer,Hayrettin Tumani,Arthur Melms,Corinna Trebst,Martin Stangel,Martin Marziniak,Frank Hoffmann,Sven Schippling,Jürgen H. Faiss,Oliver Neuhaus,Barbara Ettrich,Christian Zentner,Kersten Guthke,Ulrich Hofstadt-van Oy,Reinhard Reuss,Hannah L. Pellkofer,Ulf Ziemann,Peter Kern,Klaus Peter Wandinger,Florian Then Bergh,Tobias Boettcher,Stefan Langel,Martin Liebetrau,Paulus S. Rommer,Sabine Niehaus,Christoph Münch,Alexander Winkelmann,Uwe K Zettl U,Imke Metz,Christian Veauthier,Jörn P Sieb,C. Wilke,Hans Hartung,Orhan Aktas,Friedemann Paul +50 more
TL;DR: This study provides an overview of the clinical and paraclinical features of NMOSD in Caucasians and demonstrates a number of distinct disease characteristics in seropositive and seronegative patients.
Journal ArticleDOI
Prognostic factors and disease course in aquaporin-4 antibody-positive patients with neuromyelitis optica spectrum disorder from the United Kingdom and Japan
J Kitley,Maria Isabel Leite,Ichiro Nakashima,Patrick Waters,B McNeillis,R Brown,Yoshiki Takai,Toshiyuki Takahashi,Tatsuro Misu,Liene Elsone,Mark Woodhall,Jithin George,Mike Boggild,Angela Vincent,Anu Jacob,Kazuo Fujihara,Jacqueline Palace +16 more
TL;DR: Age at disease onset and genetic factors are both likely to be important in determining clinical outcomes in aquaporin-4 disease, since clinical features and outcomes appear not to be generic across populations and may need to be tailored to individual groups.
Journal ArticleDOI
Short delay to initiate plasma exchange is the strongest predictor of outcome in severe attacks of NMO spectrum disorders
Mickael Bonnan,Rudy Valentino,Stéphane Debeugny,Harold Merle,Jean-Louis Fergé,Hossein Mehdaoui,Philippe Cabre +6 more
TL;DR: An improved clinical benefit of early initiation of PLEX during severe attacks of NMO-SD is confirmed, suggesting that perceiving PleX as a rescue therapy only after steroid failure could be deleterious.