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Clustering Fiber Traces Using Normalized Cuts.

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TLDR
A simple and yet effective method for pairwise comparison of fiber traces is presented which in combination with the N cut criterion is shown to produce plausible segmentations of both synthetic and real fiber trace data.
Abstract
In this paper we present a framework for unsupervised segmentation of white matter fiber traces obtained from diffusion weighted MRI data. Fiber traces are compared pairwise to create a weighted undirected graph which is partitioned into coherent sets using the normalized cut (Ncut) criterion. A simple and yet effective method for pairwise comparison of fiber traces is presented which in combination with the Ncut criterion is shown to produce plausible segmentations of both synthetic and real fiber trace data. Segmentations are visualized as colored stream-tubes or transformed to a segmentation of voxel space, revealing structures in a way that looks promising for future explorative studies of diffusion weighted MRI data.

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Journal ArticleDOI

Automatic Tractography Segmentation Using a High-Dimensional White Matter Atlas

TL;DR: A new white matter atlas creation method that learns a model of the common white matter structures present in a group of subjects, enabling group comparison of white matter anatomy and results regarding the stability of the method and parameter choices are presented.
Journal ArticleDOI

QuickBundles, a Method for Tractography Simplification

TL;DR: A simple, compact, tailor-made clustering algorithm, QuickBundles (QB), that overcomes the complexity of these large data sets and provides informative clusters in seconds and can help in the search for similarities across several subjects.
Journal ArticleDOI

Corpus callosal connection mapping using cortical gray matter parcellation and DT-MRI

TL;DR: The probabilistic subdivision of the corpus callosum by connecting cortical gray matter provides a more precise understanding of the CC.
Book

Visualization in Medicine: Theory, Algorithms, and Applications

Bernhard Preim, +1 more
TL;DR: Visualization in Medicine is the first book on visualization and its application to problems in medical diagnosis, education, and treatment and describes the algorithms, the applications and their validation, and the clinical evaluation (are the techniques useful?).
Proceedings ArticleDOI

Evaluation of fiber clustering methods for diffusion tensor imaging

TL;DR: This work proposes a framework to validate clustering methods for white-matter fibers using a new measure to assess the difference between the ground truth and the clusterings, and evaluated different clustering algorithms including shared nearest neighbor clustering, which has not been used before for this purpose.
References
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Journal ArticleDOI

Normalized cuts and image segmentation

TL;DR: This work treats image segmentation as a graph partitioning problem and proposes a novel global criterion, the normalized cut, for segmenting the graph, which measures both the total dissimilarity between the different groups as well as the total similarity within the groups.
Journal ArticleDOI

Medical image analysis: progress over two decades and the challenges ahead

TL;DR: A look at progress in the field over the last 20 years is looked at and some of the challenges that remain for the years to come are suggested.
Journal ArticleDOI

MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders.

TL;DR: A magnetic resonance (MR) method to image intravoxel incoherent motions (IVIMs) by using appropriate gradient pulses and nonuniform slow flow of cerebrospinal fluid appeared as a useful feature on IVIM images.
Journal ArticleDOI

In vivo fiber tractography using DT-MRI data

TL;DR: Fiber tract trajectories in coherently organized brain white matter pathways were computed from in vivo diffusion tensor magnetic resonance imaging (DT‐MRI) data, and the method holds promise for elucidating architectural features in other fibrous tissues and ordered media.
Journal ArticleDOI

Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging

TL;DR: The results provide the first quantitative demonstration of reliable inference of anatomical connectivity between human gray matter structures using diffusion data and the first connectivity-based segmentation of gray matter.
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