Combined surgery, radiotherapy, and regional chemotherapy in carcinoma of the paranasal sinuses.
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No total resection of the maxilla has been required even in advanced cases since May 1965 and the curtailment of surgery increased the number of patients who rehabilitated successfully and were able to return to their occupations soon after the treatment.Abstract:
Since 1964, we have been using the simultaneous combined therapy of surgery, radiotherapy, and regional chemotherapy in treating malignant tumors of the paranasal sinuses. Total number of cases treated was 68. In 57 cases of carcinomas 38 showed disappearance of tumor by this therapy and among these, 22 required no further treatment. In 19 cases of still existing tumor at the end of the therapy, partial resection of the maxilla or intracavitary irradiation was effective in eradicating the residue of the tumor. Thus, no total resection of the maxilla has been required even in advanced cases since May 1965. This therapy reduced the rate of local recurrences and consequently has been improving survival rate. The curtailment of surgery increased the number of patients who rehabilitated successfully and were able to return to their occupations soon after the treatment.read more
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References
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Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
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Preoperative versus postoperative radiation in the treatment of squamous carcinoma of the paranasal sinuses
TL;DR: No significant difference was observed in the number of locally recurrent tumors or the survival rate of the patients or the relative effectiveness of pre- and postoperative radiotherapy.
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Malignant disease of the paranasal sinuses and nasal cavity. Importance of precise localization of extent of disease.
TL;DR: Detailed roentgenographic examinations are required in order to give the maximal amount of information with respect to the total extent of tumor involvement.