Comments on ‘KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease’
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TLDR
‘KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease’ fills a gap, now including very recent and new insights into the diagnosis and therapy of chronic renal disease.About:
This article is published in Kidney International.The article was published on 2013-09-01 and is currently open access. It has received 945 citations till now. The article focuses on the topics: Kidney disease & Guideline.read more
Citations
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Journal ArticleDOI
Diabetic kidney disease
Merlin C. Thomas,Michael Brownlee,Katalin Susztak,Kumar Sharma,Karin Jandeleit-Dahm,Sophia Zoungas,Peter Rossing,Per-Henrik Groop,Mark E. Cooper +8 more
TL;DR: What is now known about the molecular pathogenesis of CKD in patients with diabetes and the key pathways and targets implicated in its progression are summarized and the opportunities to develop new interventions through urgently needed investment in dedicated and focused research are explored.
Journal ArticleDOI
The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease
TL;DR: The brain–gut–kidney axis involves connections between these organs that are mediated by descending autonomic regulation from the brain and signals from the gut and the kidney, such as immune products and microbial metabolites.
Journal ArticleDOI
Update of pathophysiology and management of diabetic kidney disease
TL;DR: In this article, a review of recent large studies about diabetic kidney disease is also summarized, including new types of glucose-lowering agents, pentoxifylline, vitamin D analog paricalcitol, pyridoxamine, ruboxistaurin, soludexide, Janus kinase inhibitors and nonsteroidal minerocorticoid receptor antagonists.
Journal ArticleDOI
The systemic nature of CKD
Carmine Zoccali,Raymond Vanholder,Ziad A. Massy,Alberto Ortiz,Pantelis Sarafidis,Friedo W. Dekker,Danilo Fliser,Denis Fouque,Gunnar H. Heine,Kitty J Jager,Mehmet Kanbay,Francesca Mallamaci,Gianfranco Parati,Patrick Rossignol,Andrzej Wiecek,Gérard M. London +15 more
TL;DR: A systems biology approach to CKD using omics techniques will hopefully enable in-depth study of the pathophysiology of this systemic disease, and has the potential to unravel critical pathways that can be targeted for CKD prevention and therapy.
Journal ArticleDOI
Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD
Gerald Schulman,Tomas Berl,Gerald J. Beck,Giuseppe Remuzzi,Eberhard Ritz,Kiyoshi Arita,Akira Kato,Miho Shimizu +7 more
TL;DR: The benefit of adding AST-120 to standard therapy in patients with moderate to severe CKD is not supported by these data, and disease progression was more gradual than expected in the trial populations.
References
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Plasma aldosterone regulation in anephric man.
W. Gordon Walker,C. Robert Cooke +1 more
Book
Oxford textbook of clinical nephrology
TL;DR: Oxford textbook of clinical nephrology, Oxford textbook of Clinical Nephrology , کتابجیتال جندی شاپور اهواز
Journal ArticleDOI
Nephrotoxicity of contrast media.
TL;DR: A 64-year-old man was admitted to the hospital for evaluation of progressive dyspnea and increasing angina and showed normal sinus rhythm and evidence of an old, anteroseptal myocardial infarction.
Journal ArticleDOI
Invasive group B Streptococcal disease in non-pregnant adults : a review with emphasis on skin and soft-tissue infections.
TL;DR: The epidemiology, pathogenesis and treatment of invasive GBS disease in non-pregnant adults, with an emphasis on skin and soft-tissue infections is reviewed, including necrotizing fasciitis and toxic shock syndrome.
Journal ArticleDOI
Cephalosporin-Induced Neurotoxicity: Clinical Manifestations, Potential Pathogenic Mechanisms, and the Role of Electroencephalographic Monitoring
Marie F. Grill,Rama Maganti +1 more
TL;DR: Knowledge and awareness of the neurotoxic clinical manifestations, EEG findings, and underlying mechanisms are essential for clinicians in identifying and treating this potentially lethal but reversible complication of cephalosporin therapy.
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