Journal ArticleDOI
Common-path interferometer for frequency-domain optical coherence tomography.
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TLDR
A Michelson-type spectral interferometer that uses a common beam path for the reference and the sample arms is described, which is well suited for frequency-domain optical coherence tomography of biological samples.Abstract:
A Michelson-type spectral interferometer that uses a common beam path for the reference and the sample arms is described. This optical arrangement is more compact and stable than the more commonly used dual-arm interferometer and is well suited for frequency-domain optical coherence tomography of biological samples. With a 16-bit CCD camera, the instrument has sufficient dynamic range and resolution for imaging to depths of 2 mm in scattering biological materials. Images obtained with this spectral interferometer are presented, including cross-sectional images in a Xenopus laevis tadpole.read more
Citations
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Patent
Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
TL;DR: In this paper, a method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (LCI) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies, is presented.
Patent
Method and apparatus for performing optical imaging using frequency-domain interferometry
TL;DR: In this article, the first and/or second electro-magnetic radiations have a spectrum whose mean frequency changes substantially continuously over time at a tuning speed that is greater than 100 Tera Hertz per millisecond.
Patent
System and method for optical coherence imaging
TL;DR: In this paper, a system and method for imaging of a sample, e.g., biological sample, are provided, where at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated.
Journal ArticleDOI
Imaging the subcellular structure of human coronary atherosclerosis using micro–optical coherence tomography
Linbo Liu,Joseph A. Gardecki,Seemantini K. Nadkarni,Seemantini K. Nadkarni,Jimmy Toussaint,Yukako Yagi,Brett E. Bouma,Brett E. Bouma,Guillermo J. Tearney,Guillermo J. Tearney +9 more
TL;DR: It is shown that μOCT images of cadaver coronary arteries provide clear pictures of cellular and subcellular features associated with atherogenesis, thrombosis and responses to interventional therapy, and suggests that μ OCT can complement existing diagnostic techniques for investigating atherosclerotic specimens, and may eventually become a useful tool for cellular andSubcellular characterization of the human coronary wall in vivo.
PatentDOI
Speckle reduction in optical coherence tomography by path length encoded angular compounding
TL;DR: In this paper, the angular compounding by path length encoding (ACPE) algorithm is proposed to reduce speckle in OCT images by averaging images obtained at different incident angles, with each image encoded by the path length.
References
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Journal ArticleDOI
Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Journal ArticleDOI
Optical Coherence Tomography
TL;DR: The optical coherence tomograph is a new, noninvasive technical device that can obtain cross-sectional, high-resolution images-optical coherencetomographs (OCT)-of the retina that permits an accurate evaluation of various macular and chorioretinal pathologies and the early detection of glaucomatous damage.
Journal ArticleDOI
In vivo ultrahigh-resolution optical coherence tomography.
Wolfgang Drexler,Uwe Morgner,Franz X. Kärtner,Costas Pitris,Stephen A. Boppart,Xingde Li,Erich P. Ippen,James G. Fujimoto +7 more
TL;DR: To overcome depth-of-field limitations the authors perform zone focusing and image fusion to construct a tomogram with high transverse resolution throughout the image depth, which is to their knowledge the highest longitudinal resolution demonstrated to date for in vivo OCT imaging.
Journal ArticleDOI
Linear techniques of phase measurement by femtosecond spectral interferometry for applications in spectroscopy
TL;DR: In this article, dual-quadrature spectral interferometry and Fourier transform (FT) were used to obtain a complete measurement of the complex electric field, E(ω), as a continuous function of frequency.
Journal ArticleDOI
"Coherence radar" and "spectral radar"-new tools for dermatological diagnosis.
G Ha Usler,M W Lindner +1 more
TL;DR: In vivo measurements of human skin by a fiber optical implementation of the sensor based on short coherence interferometry are demonstrated and in vivo 3-D mapping of naked skin was performed without preparation.