Computational Methods in Drug Discovery
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Cites background from "Computational Methods in Drug Disco..."
...However, the high costs required to establish and maintain these screening platforms often hamper their use for drug discovery [1]....
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Cites background from "Computational Methods in Drug Disco..."
...basis of their therapeutic values and to predict possible derivatives that would improve activity [283]....
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References
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"Computational Methods in Drug Disco..." refers methods in this paper
...In the first step, the target sequence is used as a query for the identification of template structures in the PDB. Templates with high sequence similarity can be determined by a straightforward PDB-BLAST search (Altschul et al., 1990)....
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...mined by a straightforward PDB-BLAST search (Altschul et al., 1990)....
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"Computational Methods in Drug Disco..." refers methods in this paper
...Search for template structure is followed by sequence alignment using methods like ClustalW (Thompson et al., 1994), which is a multiple sequence alignment tool....
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