Journal ArticleDOI
Concise, Stereoselective Approach to the Spirooxindole Ring System of Citrinadin A
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TLDR
The spirooxindole ring system of citrinadin A has been synthesized with excellent control over the absolute stereochemistry at the spirocenter using a novel diastereoselective DMDO-mediated oxidative rearrangement employing an 8-phenylmenthol chiral auxiliary on the indole nitrogen.About:
This article is published in Organic Letters.The article was published on 2007-10-06. It has received 66 citations till now. The article focuses on the topics: Ring (chemistry).read more
Citations
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Highly Enantioselective [3+2] Annulation of Morita–Baylis–Hillman Adducts Mediated by L‐Threonine‐Derived Phosphines: Synthesis of 3‐Spirocyclopentene‐2‐oxindoles having Two Contiguous Quaternary Centers
TL;DR: The Morita-Baylis-Hillman (MBH) carbonates (II, (IV), and (VII) serve as C3 synthons in asymmetric [3 + 2] annulation reactions to give a series of 3-spirocyclopentene-2-oxindoles with two contiguous quaternary centers such as (III, (V), or (VIII) as present in various alkaloids as discussed by the authors.
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Advances in dearomatization strategies of indoles
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Molecular diversity of spirooxindoles. Synthesis and biological activity
TL;DR: This review focuses on the various strategies for the enantioselective synthesis of spirocyclic oxindoles relying on reports over the past decade and from earlier work.
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Palladium‐Catalyzed Tandem Heck Reaction/C ? H Functionalization—Preparation of Spiro‐Indane‐Oxindoles
TL;DR: An efficient preparation of spiro-fused indane-oxindoles by carbopalladation to form an alkylpalladium intermediate and subsequent functionalization of an unactivated aryl C H bond is reported.
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Methods for direct alkene diamination, new & old
TL;DR: The purpose of this review is to provide an overview of all methods of direct alkene diamination, metal-mediated or otherwise.
References
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Palladium- or nickel-catalyzed cross coupling. A new selective method for carbon-carbon bond formation
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Marine-derived fungi: a chemically and biologically diverse group of microorganisms
Tim S. Bugni,Chris M. Ireland +1 more
TL;DR: A diverse array of secondary metabolites have been isolated and characterized from marine-derived fungi and the structures and biological activities of these metabolites are presented.
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Asymmetric hydroxylation of enolates with N-sulfonyloxaziridines
Franklin A. Davis,Bang Chi Chen +1 more
TL;DR: Davis as discussed by the authors was a pioneer in asymmetric synthesis, and developed a new method for stereoselective fluorination of organic molecules, which is a recent focus of his research at Drexel University.
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An Efficient Catalytic Asymmetric Epoxidation Method
TL;DR: In this paper, a catalytic asymmetric epoxidation method for olefins using potassium peroxomonosulfate (Oxone, Dupont) as oxidant and a fructose-derived ketone (1) as catalyst is described.
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Paraherquamides, brevianamides, and asperparalines: laboratory synthesis and biosynthesis. An interim report.
Robert M. Williams,Rhona J. Cox +1 more