Conformations of immunoglobulin hypervariable regions.
Citations
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Additional excerpts
...The database search approach to loop modeling is accurate and efficient when a specific set of loops is created to address the modeling of that class of loops, such asβ-hairpins (167) and the hypervariable regions in immunoglobulins (36)....
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...The database approach to loop prediction consists of finding a segment of main chain that fits the two stem regions of a loop (36, 60, 85, 122, 142, 166, 178, 198)....
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3,006 citations
Cites background from "Conformations of immunoglobulin hyp..."
...…and efficient when a database of specific loops is created to address the modeling of the same class of loops, such as β-hairpins (Sibanda et al., 1989), or loops on a specific fold, such as the hypervariable regions in the immunoglobulin fold (Chothia and Lesk, 1987; Chothia et al., 1989)....
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2,604 citations
1,999 citations
Cites background or methods from "Conformations of immunoglobulin hyp..."
...The database search approach to loop modeling is accurate and efficient when a specific set of loops is created to address the modeling of that class of loops, such asb-hairpins~Sibanda et al., 1989! and the hypervariable regions in immunoglobulins~Chothia & Lesk, 1987; Chothia et al., 1989!....
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...…a segment of main chain that fits the two stem regions of a loop ~Greer, 1980; Cohen et al., 1986; Jones & Thirup, 1986; Chothia & Lesk, 1987; Chothia et al., 1989; Tramontano et al., 1989; Summers & Karplus, 1990; Levitt, 1992; Tramontano & Lesk, 1992; Topham et al., 1993; Lessel &…...
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References
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