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Journal ArticleDOI

Congenital malabsorption of folate

Philip Lanzkowsky
- 01 May 1970 - 
- Vol. 48, Iss: 5, pp 580-583
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TLDR
Three siblings and a twenty year old girl have been recorded by two different groups of investigators as having congenital isolated defects of gastrointestinal absorption of folic acid, resulting in recurrent megaloblastic anemia and associated with mental retardation, convulsions and a neurologic movement disorder.
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This article is published in The American Journal of Medicine.The article was published on 1970-05-01. It has received 77 citations till now. The article focuses on the topics: Folic acid transport & Megaloblastic anemia.

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Citations
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Journal ArticleDOI

Laboratory Tests for the Assessment of Nutritional Status

TL;DR: The CRC Critical Reviews in Clinical Laboratory Sciences: Vol. 4, No. 3, No 3, pp 215-340 as discussed by the authors was the first publication of a comprehensive review of laboratory tests for the assessment of nutritional status.
Journal ArticleDOI

Vitamin homeostasis in the central nervous system.

TL;DR: Several groups of investigators have suggested that pharmacologic doses of certain water-soluble vitamins, including vitamins B6, B12 and C and niacin, may be useful in the treatment of schizophrenic patients.
Book ChapterDOI

The Hematopoietic System

TL;DR: Anemia is probably the commonest effect of nutritional deficiency in human beings and has certainly been the most extensively studied.
Journal ArticleDOI

Occipital epilepsies: identification of specific and newly recognized syndromes

TL;DR: In this article, the identification of idiopathic generalized epilepsies of childhood and adolescence was discussed, including malformations of cortical development, vascular, metabolic, and metabolic disorders.
References
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Journal ArticleDOI

Aseptic addition method for Lactobacillus casei assay of folate activity in human serum

TL;DR: In this article, an enzyme addition method is described for a microbiological assay with Lactobacillis casei of folate activity in human serum, where the manipulations involved in the assay are halved, by deleting autoclaving of serum in buffers.
Journal ArticleDOI

Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients

E.H. Reynolds
- 20 May 1967 - 
TL;DR: It is concluded that folic acid partially reverses both the therapeutic (antiepileptic) and retarding effects of phenobarbitone, phenytoin, and primidone.
Journal ArticleDOI

Megaloblastic anaemia due to phenobarbitone; the convulsant action of therapeutic doses of folic acid.

TL;DR: It has been shown that adult patients in this hospital are more likely to develop staphylococcal sepsis if they are nasal carriers of Staph.
Journal ArticleDOI

The absorption and malabsorption of folic acid and its polyglutamates

TL;DR: Evidence indicates that folic polyglutamate is malabsorbed to a greater degree than free folic acid, suggesting that intestinal conjugase deficiency or inhibition may play an important role in pathogenesis of this malabsorptive disorder.
Journal ArticleDOI

Anticonvulsant therapy, megaloblastic haemopoiesis and folic acid metabolism

TL;DR: It was found that neither morphological changes in the peripheral blood nor biochemical investigations were reliable indications of megaloblastic haemopoiesis, and all three major anticonvulsant drugs appear to be capable of causing folate deficiency.
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