Journal ArticleDOI
Conservation of gene structure and arrangement between vaccinia virus and orf virus.
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The OV ORFs are arranged on the genome in an almost identical manner to their VAC counterparts revealing the common evolutionary origin of the two viruses despite the extreme difference in their G+C content.About:
This article is published in Virology.The article was published on 1993-07-01. It has received 60 citations till now. The article focuses on the topics: Open reading frame & ORFS.read more
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The complete genomic sequence of the modified vaccinia ankara strain : comparison with other orthopoxviruses
TL;DR: The attenuated phenotype of MVA is the result of numerous mutations, particularly affecting the host interactive proteins, including the ankyrin-like genes, but also involving some structural proteins.
Journal ArticleDOI
Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus.
TL;DR: A gene encoding a polypeptide with homology to mammalian vascular endothelial growth factors (VEGFs) has been discovered in the genome of orf virus (OV), a parapoxvirus that affects sheep and goats and, occasionally, humans.
Journal ArticleDOI
Genomes of the Parapoxviruses Orf Virus and Bovine Papular Stomatitis Virus
G. Delhon,G. Delhon,Edan R. Tulman,Claudio L. Afonso,Z. Lu,A. de la Concha-Bermejillo,Howard D. Lehmkuhl,Maria E. Piccone,Gerald F. Kutish,Daniel L. Rock +9 more
TL;DR: Compared to other mammalian chordopoxviruses, PPV shares unique genomic features with molluscum contagiosum virus, including a G+C-rich nucleotide composition, three orthologous genes, and a paucity of nucleotide metabolism genes.
Journal ArticleDOI
The genome of molluscum contagiosum virus: Analysis and comparison with other poxviruses
Tatiana G. Senkevich,Eugene V. Koonin,Joachim Jakob Bugert,Joachim Jakob Bugert,Gholamreza Darai,Bernard Moss +5 more
TL;DR: Despite the acquisition of unique genes for host interactions and changes in GC content, the physical order and regulation of essential ancestral poxvirus genes have been largely conserved in MCV and OPV.
Journal ArticleDOI
A homolog of interleukin-10 is encoded by the poxvirus orf virus.
TL;DR: A gene encoding a polypeptide with homology to interleukin-10 (IL-10) has been discovered in the genome of orf virus (OV) strain NZ2, a parapoxvirus that infects sheep, goats, and humans.