Consumption of ultra-processed foods and cancer risk: results from NutriNet-Santé prospective cohort
Thibault Fiolet,Bernard Srour,Laury Sellem,Emmanuelle Kesse-Guyot,Benjamin Allès,Caroline Méjean,Mélanie Deschasaux,Philippine Fassier,Paule Latino-Martel,Marie Beslay,Serge Hercberg,Céline Lavalette,Carlos Augusto Monteiro,Chantal Julia,Mathilde Touvier +14 more
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TLDR
In this large prospective study, a 10% increase in the proportion of ultra-processed foods in the diet was associated with a significant increase of greater than 10% in risks of overall and breast cancer.Abstract:
Objective To assess the prospective associations between consumption of ultra-processed food and risk of cancer. Design Population based cohort study. Setting and participants 104 980 participants aged at least 18 years (median age 42.8 years) from the French NutriNet-Sante cohort (2009-17). Dietary intakes were collected using repeated 24 hour dietary records, designed to register participants’ usual consumption for 3300 different food items. These were categorised according to their degree of processing by the NOVA classification. Main outcome measures Associations between ultra-processed food intake and risk of overall, breast, prostate, and colorectal cancer assessed by multivariable Cox proportional hazard models adjusted for known risk factors. Results Ultra-processed food intake was associated with higher overall cancer risk (n=2228 cases; hazard ratio for a 10% increment in the proportion of ultra-processed food in the diet 1.12 (95% confidence interval 1.06 to 1.18); P for trend Conclusions In this large prospective study, a 10% increase in the proportion of ultra-processed foods in the diet was associated with a significant increase of greater than 10% in risks of overall and breast cancer. Further studies are needed to better understand the relative effect of the various dimensions of processing (nutritional composition, food additives, contact materials, and neoformed contaminants) in these associations. Study registration Clinicaltrials.gov NCT03335644.read more
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The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report
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Kevin D. Hall,Alexis Ayuketah,Robert J. Brychta,Hongyi Cai,Thomas M. Cassimatis,Kong Y. Chen,Stephanie T. Chung,Elise Costa,Amber B. Courville,Valerie L. Darcey,Laura A. Fletcher,Ciarán G. Forde,Ahmed M. Gharib,Juen Guo,Rebecca Howard,Paule V. Joseph,Suzanne McGehee,Ronald Ouwerkerk,Klaudia Raisinger,Irene Rozga,Michael Stagliano,Mary Walter,Peter Walter,Shanna Yang,Megan Zhou +24 more
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Individuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships.
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Ultra-processed food intake and risk of cardiovascular disease: prospective cohort study (NutriNet-Santé)
Bernard Srour,Léopold Fezeu,Emmanuelle Kesse-Guyot,Benjamin Allès,Caroline Méjean,Roland M. Andrianasolo,Eloi Chazelas,Mélanie Deschasaux,Serge Hercberg,Pilar Galan,Carlos Augusto Monteiro,Chantal Julia,Mathilde Touvier +12 more
TL;DR: Higher consumption of ultra-processed foods was associated with higher risks of cardiovascular, coronary heart, and cerebrovascular diseases, and further studies are needed to understand better the relative contributions.
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