Continuous Glucose Monitoring vs Conventional Therapy for Glycemic Control in Adults With Type 1 Diabetes Treated With Multiple Daily Insulin Injections: The GOLD Randomized Clinical Trial.
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Cites background from "Continuous Glucose Monitoring vs Co..."
...A1C is currently recognized as the key surrogate marker for the development of long-termdiabetes complications in people with type 1 and type 2 diabetes and has been used as the primary end point for many CGM studies (1,3,4,6,33,34)....
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"Continuous Glucose Monitoring vs Co..." refers background or methods in this paper
...A keystone in preventing diabetic complications in patients with type 1 diabetes is good glycaemic control (1)....
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...Suchtrialshave, forexample, consisted only of patients with the following characteristics: (1) continuous subcutaneous insulin infusions; (2) initiated CGMandcontinuous subcutaneous insulin infusions simultaneously; or (3) includedpatientswithbothmultipledaily insulininjectionsandcontinuoussubcutaneousinsulininfusions....
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...Other reasons for the CGM-first group were dermatological reaction (1), preference to continuing use of CGM (2), preference to switch to insulin pump (1), paracetamol (acetaminophen) use for shoulder pain (1), and unwillingness to proceed (1); for the conventional therapy–first group, other reasons were lack of time (1) and patient request (1)....
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...27 The theory of sequentially multiple test procedures (1) will be applied for the primary analysis and for the 4 first secondary analyses....
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