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Correlation between Antibacterial Power and Chemical Structure of Higher Alkyl Ammonium Ions.

E. I. Valko, +1 more
- 01 Oct 1945 - 
- Vol. 50, Iss: 4, pp 481-490
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TLDR
This paper presents additional data gathered on series of compounds closely related to polymethine-like cations that have shown the germicidal efficacy of surface-active cations.
Abstract
The relation between the chemical structure and the germicidal efficacy of surface-active cations has been discussed by several investigators (Eldred and Niederl, 1941; Epstein et al., 1943; Jerchel, 1942, 1943; Kolloff et al., 1942; Kuhn et al., 1940, 5 papers; 1941; Rawlins et al., 1943; Shelton et al., 1939, 1940; Westphal, 1941; Woodruff et al., 1942) during the last few years. This paper presents additional data gathered on series of compounds closely related to

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Journal ArticleDOI

Antimicrobial activity of some alkyltrimethylammonium bromides

TL;DR: Data indicated that whilst the level of activity was generally parabolically related to n‐alkyl chain length, separate dependencies existed for short and long chain substituents, with disproportionately large increases in activity, in the order of three log cycles, occurring as substituent chain lengths increased from n = 10 to n = 12.
Journal ArticleDOI

Neutralization of antimicrobial chemicals by recovery media

TL;DR: Both formulations of D/E medium show promise for studying and evaluating known and unknown compounds, mixtures and formulations of antimicrobial chemicals.
Journal ArticleDOI

Diacyl glycerol arginine-based surfactants: biological and physicochemical properties of catanionic formulations.

TL;DR: A catanionic vesicles-based strategy to reduce the cytotoxicity of the diacyl glycerol arginine-based synthetic surfactants is reported, constituting a proof of principle that tuning formulation can reduce the cytoplasmic activity of many Surfactants, opening their possible biological applications.
Journal ArticleDOI

Mixed monolayer of DPPC and lysine-based cationic surfactants: An investigation into the antimicrobial activity

TL;DR: Compression π-A isotherms of mixtures of DPPC/lysine surfactants at different pH showed an expansion of the DPPC monolayer, suggesting cationic lysine Surfactant/DPPC interactions, which strongly depend on surfactant structure and hydrophobic interactions.
References
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Journal ArticleDOI

The Antibacterial Action of Surface Active Cations.

TL;DR: Observations on the reversibility of the antibacterial effect of the surfaceactive cations, and on the protective action on bacteria exerted by relatively harmless cations against the action of toxic cations indicate that there is a close relationship between the antib bacterial behavior of metallic and dye cations and that of surface- active cations.
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