COVID-19 and Cancer Therapy: Interrelationships and Management of Cancer Cases in the Era of COVID-19
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TLDR
The challenges and health risks facing cancer patients and cancer treatment in the COVID-19 context are delve into, with suggestions into viable measures which can be taken to minimize exposure to the risk of contracting CO VID-19 for this vulnerable subgroup.Abstract:
The COVID-19 global epidemic poses this generation's biggest worldwide public health challenge probably since the 1918 influenza epidemic. Recent reports on two new variants have triggered a dramatic upsurge in research to understand the pandemic, primarily focussing on the virology, triggers, clinical characteristics, and diagnostic tests including the prevention and management of the novel coronavirus. Whilst such studies are important in managing the present medical emergency, there is a need for further work to include interdependencies between the epidemic and other illnesses. This will help in developing effective approaches to treat and manage associated diseases in both the short and the long term. In this regard, people living with cancer are a subgroup that is highly vulnerable to respiratory infections and acute pneumonitis similar to the one caused by the COVID-19 virus. This is because the state of their immunity is compromised due to malignancy and the adverse effects of anticancer treatments. With annual cancer projections rising globally and an estimated 70 percent of all cancer-related deaths occurring in low- and middle-income countries, the patient population with impaired immune systems that could be adversely impacted by COVID-19 is only anticipated to rise. In this review, we delve into the challenges and health risks facing cancer patients and cancer treatment in the COVID-19 context, with suggestions into viable measures which can be taken to minimize exposure to the risk of contracting COVID-19 for this vulnerable subgroup. New mutations and the prospects offered by vaccines development and how they relate to this class of patients are also discussed. [ABSTRACT FROM AUTHOR] Copyright of Journal of Chemistry is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)read more
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References
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Journal ArticleDOI
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
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Wenhua Liang,Wei-jie Guan,Ruchong Chen,Wei Wang,Jianfu Li,Ke Xu,Caichen Li,Qing Ai,Weixiang Lu,Hengrui Liang,Shiyue Li,Jianxing He +11 more
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Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study.
Tao Chen,Di Wu,Huilong Chen,Weiming Yan,Danlei Yang,Guang Chen,Ke Ma,Dong Xu,Haijing Yu,Hongwu Wang,Tao Wang,Wei Guo,Jia Chen,Chen Ding,Xiaoping Zhang,Jiaquan Huang,Meifang Han,Shusheng Li,Xiaoping Luo,Jianping Zhao,Qin Ning +20 more
TL;DR: Severe acute respiratory syndrome coronavirus 2 infection can cause both pulmonary and systemic inflammation, leading to multi-organ dysfunction in patients at high risk, including patients with cardiovascular comorbidity.
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Jing Yang,Ya Zheng,Xi Gou,Ke Pu,Zhaofeng Chen,Qinghong Guo,Rui Ji,Haojia Wang,Yuping Wang,Yongning Zhou +9 more
TL;DR: The prevalence of comorbidities in infected patients and risk factors for severe compared with non-severe patients are assessed to help the health sector guide vulnerable populations and assess the risk of deterioration.