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Open AccessJournal ArticleDOI

COVID-19 and Decompressive Hemicraniectomy for Acute Ischemic Stroke.

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TLDR
A positive test for COVID-19 should not be used in isolation to exclude patients from a potentially lifesaving procedure, and patients with large hemispheric stroke can have a good outcome with decompressive hemicraniectomy.
Abstract
Background and Purpose: Young patients with malignant cerebral edema have been shown to benefit from early decompressive hemicraniectomy. The impact of concomitant infection with coronavirus diseas...

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Citations
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Journal ArticleDOI

COVID-19 and Cerebrovascular Diseases: A Systematic Review and Perspectives for Stroke Management.

TL;DR: Cerebrovascular events are relatively common findings in COVID-19 infection, and they could have a multifactorial etiology, and more accurate and prospective data are needed to better understand the impact of cerebrov vascular events in COIDs.
Journal ArticleDOI

Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives

TL;DR: From pharmacological and cardiovascular perspectives, the treatment of COVID-19 with chloroquine and its derivatives should be systematically evaluated, and patients should be routinely monitored for cardiovascular conditions to prevent lethal adverse events.
Journal ArticleDOI

Severe Neurologic Complications of SARS-CoV-2

TL;DR: A review of the literature of severe neurologic complications of SARS-CoV-2 and cases from our institution to illustrate these conditions can be found in this article, however, the true prevalence is unknown.
Journal ArticleDOI

Geospatial Distribution of Neurosurgeons Age 60 and Older Relative to the Spread of COVID-19.

TL;DR: In this paper, the authors performed an ecological study to analyze the geospatial distribution of neurosurgeons ≥ 60 years old and compare these data with the spread of 2019 novel coronavirus disease (COVID-19) across the United States.
References
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Journal ArticleDOI

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.

TL;DR: Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.
Journal ArticleDOI

Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY). A Randomized, Controlled Trial

TL;DR: DESTINY showed that hemicraniectomy reduces mortality in large hemispheric stroke, and the steering committee decided to terminate the trial in light of the results of the joint analysis of the 3 European hemicaniectomy trials.
Journal ArticleDOI

Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial

TL;DR: Surgical decompression reduces case fatality and poor outcome in patients with space-occupying infarctions who are treated within 48 h of stroke onset and there is no evidence that this operation improves functional outcome when it is delayed for up to 96 h after stroke onset.
Journal ArticleDOI

Sequential-Design, Multicenter, Randomized, Controlled Trial of Early Decompressive Craniectomy in Malignant Middle Cerebral Artery Infarction (DECIMAL Trial)

TL;DR: In this trial, early decompressive craniectomy increased by more than half the number of patients with moderate disability and very significantly reduced the mortality rate compared with that after medical therapy.
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