COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options.
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"COVID-19 and the cardiovascular sys..." refers background in this paper
...9 Coronavirus receptor binding occurs via the spike protein (encoded by the structural S gene) which has two subunits....
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...9 SARS-CoV-2 has a higher affinity for binding to ACE2 than SARS-CoV, and binding involves a larger number of interaction sites....
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"COVID-19 and the cardiovascular sys..." refers background or result in this paper
...Other non-specific symptoms have also been reported, which included nasal congestion, rhinorrhea, sore throat, myalgia, poor appetite, and diarrhoea.(21) Fever and cough typically appear concomitantly, followed by shortness of breath and severe fatigue, which appear around day 6–7(6) and are associated with development of severe bilateral (and occasional unilateral) pneumonia (Figure 4)....
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...For example, a large number of healthcare workers and inpatients were exposed to COVID-19 in the hospital in the early, rather than the later phase in the pandemic in China.(21) The demographics of patients in the early studies from China were different from those reported later in the largest aggregate study of COVID-19 patients by Guan et al....
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...Similar associations between cTnI elevation and disease severity are shown when analysing cohorts on the basis of the need for ICU care.(6,21) Thus patient monitoring should include a number of laboratory tests, summarized in Table 4, based on current experience and studies....
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...Data were collected as part of a retrospective study, consent was waived, and collection of these data was approved by local ethics committee of Wuhan, China....
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...For example, a large number of healthcare workers and inpatients were exposed to COVID-19 in the hospital in the early, rather than the later phase in the pandemic in China.21 The demographics of patients in the early studies from China were different from those reported later in the largest aggregate study of COVID-19 patients by Guan et al. in China22 (Table 1)....
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