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Open AccessJournal ArticleDOI

COVID-19 in solid organ transplant recipients: A single-center case series from Spain.

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TLDR
It is suggested that SARS‐CoV‐2 infection has a severe course in SOT recipients, and c‐reactive protein levels at various points were significantly higher among recipients who experienced unfavorable outcome.
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This article is published in American Journal of Transplantation.The article was published on 2020-07-01 and is currently open access. It has received 351 citations till now. The article focuses on the topics: Transplantation & Organ transplantation.

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COVID-19 in Immunocompromised Hosts: What We Know So Far.

TL;DR: This work reviews the existing literature on COVID-19 among immunocompromised populations ranging from cancer patients and solid organ transplant recipients to patients with HIV and those receiving immunomodulatory therapy for autoimmune disease and concludes that further prospective, controlled studies are needed to determine the attributable risk of Immunocompromising conditions and therapies.
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An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants.

Sophie Caillard, +65 more
- 01 Dec 2020 - 
TL;DR: Characteristics and clinical outcomes of recipients of kidney transplants included in the French nationwide Registry of Solid Organ Transplant Recipients with Covid-19 andMultivariable analysis identified overweight, fever, and dyspnea as independent risk factors for severe disease, whereas age over 60 years, cardiovascular disease, and Dyspnea were independently associated with mortality.
References
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Journal ArticleDOI

A Novel Coronavirus from Patients with Pneumonia in China, 2019.

TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI

Acute respiratory distress syndrome: the Berlin Definition.

TL;DR: The updated and revised Berlin Definition for ARDS addresses a number of the limitations of the AECC definition and may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.
Journal ArticleDOI

COVID-19: consider cytokine storm syndromes and immunosuppression

TL;DR: Re-analysis of data from a phase 3 randomised controlled trial of IL-1 blockade (anakinra) in sepsis, showed significant survival benefit in patients with hyperinflammation, without increased adverse events.
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