COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses
Muhammad Adnan Shereen,Muhammad Adnan Shereen,Suliman Khan,Abeer Kazmi,Nadia Bashir,Rabeea Siddique +5 more
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TLDR
The approaches for developing effective vaccines and therapeutic combinations to cope with this viral outbreak are discussed and the emergence and pathogenicity of COVID-19 infection and previous human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory virus (MERS- coV) is analyzed.About:
This article is published in Journal of Advanced Research.The article was published on 2020-07-01 and is currently open access. It has received 2643 citations till now. The article focuses on the topics: Coronavirus & Middle East respiratory syndrome coronavirus.read more
Citations
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response.
Indwiani Astuti,Ysrafil +1 more
TL;DR: This review provides a complete review related to structure, origin, and how the body responds to this virus infection and explains the possibility of an immune system over-reaction or cytokine storm.
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Psychological Outcomes Associated with Stay-at-Home Orders and the Perceived Impact of COVID-19 on Daily Life.
Matthew T. Tull,Keith A. Edmonds,Kayla M. Scamaldo,Julia R. Richmond,Jason P. Rose,Kim L. Gratz +5 more
TL;DR: In this article, the authors examined relations of both stay-at-home orders and the perceived impact of COVID-19 on daily life to psychological outcomes (depression, health anxiety, financial worry, social support, and loneliness) in a nationwide U.S. community adult sample.
Journal ArticleDOI
Knowledge, Attitude and Practice Toward COVID-19 Among the Public in the Kingdom of Saudi Arabia: A Cross-Sectional Study
Mohammed Khaled Al-Hanawi,Khadijah Angawi,Noor Alshareef,Ameerah M. N. Qattan,Hoda Z. Helmy,Yasmin Abudawood,Mohammed Alqurashi,Waleed M. Kattan,Nasser Akeil Kadasah,Gowokani Chijere Chirwa,Gowokani Chijere Chirwa,Omar Zayyan Alsharqi +11 more
TL;DR: The results showed that men have less knowledge, less optimistic attitudes, and less good practice toward COVID-19, than women, and targeted health education interventions should be directed to this particular vulnerable population, who may be at increased risk of contracting CO VID-19.
Journal ArticleDOI
Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions.
Yvan Jamilloux,Yvan Jamilloux,Thomas Henry,Alexandre Belot,Sébastien Viel,Maxime Fauter,Thomas El Jammal,Thierry Walzer,Bruno François,Pascal Sève +9 more
TL;DR: This review provides an overview of current knowledge on COVID-19 immunopathology, discussing the defective type-I IFN response, the theoretical role of IL-7 to restore lymphocyte repertoire, as well as reviewing current evidence drawn from clinical trials.
Journal ArticleDOI
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic.
Carsten Weiss,Marie Carrière,Laura Fusco,Laura Fusco,Ilaria Capua,Jose Angel Regla-Nava,Matteo Pasquali,James A. Scott,Flavia Vitale,Flavia Vitale,Mehmet Ünal,Cecilia Mattevi,Davide Bedognetti,Arben Merkoçi,Arben Merkoçi,Ennio Tasciotti,Ennio Tasciotti,Açelya Yilmazer,Yury Gogotsi,Francesco Stellacci,Lucia Gemma Delogu +20 more
TL;DR: Nanoimmunity by design can help to design materials for immune modulation, either stimulating or suppressing the immune response, which would find applications in the context of vaccine development for SARS-CoV-2 or in counteracting the cytokine storm, respectively.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.
Qun Li,Xuhua Guan,Peng Wu,Xiaoye Wang,Lei Zhou,Yeqing Tong,Ruiqi Ren,Kathy Leung,Eric H. Y. Lau,Jessica Y. Wong,Xuesen Xing,Nijuan Xiang,Yang Wu,Chao Li,Chen Qi,Dan Li,Tian Liu,Jing Zhao,Man Liu,Wenxiao Tu,Chuding Chen,Lianmei Jin,Rui Yang,Qi Wang,Suhua Zhou,Rui Wang,Hui Liu,Yingbo Luo,Yuan Liu,Ge Shao,Huan Li,Zhongfa Tao,Yang Yang,Yang Yang,Zhiqiang Deng,Boxi Liu,Zhitao Ma,Yanping Zhang,Guoqing Shi,Tommy Tsan-Yuk Lam,Joseph T. Wu,George F. Gao,George F. Gao,Benjamin J. Cowling,Bo Yang,Gabriel M. Leung,Zijian Feng +46 more
TL;DR: There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
Journal ArticleDOI
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
Journal ArticleDOI
A new coronavirus associated with human respiratory disease in China.
Fan Wu,Su Zhao,Bin Yu,Yan-Mei Chen,Wen Wang,Zhi gang Song,Yi Hu,Zhao Wu Tao,Jun Hua Tian,Yuan Yuan Pei,Ming Li Yuan,Yu Ling Zhang,Fa Hui Dai,Yi Liu,Qi Min Wang,Jiao Jiao Zheng,Lin Xu,Edward C. Holmes,Edward C. Holmes,Yong-Zhen Zhang,Yong-Zhen Zhang +20 more
TL;DR: Phylogenetic and metagenomic analyses of the complete viral genome of a new coronavirus from the family Coronaviridae reveal that the virus is closely related to a group of SARS-like coronaviruses found in bats in China.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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