Creatinine complexes of zinc, cadmium and mercury
TL;DR: In this paper, Zinc, cadmium and mercury(II) complexes of creatinine of the composition M(Creat) 2 X 2 (X = Cl, Br or I) are characterized by analytical and spectral methods.
About: This article is published in Polyhedron.The article was published on 1984-01-01. It has received 26 citations till now. The article focuses on the topics: Zinc & Nuclear magnetic resonance spectroscopy.
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TL;DR: In this article, the stability constants of binary complexes formed by creatinine with Cu(II, Co(II), Mn(II) and Cr(III) were determined by the Calvin-Bjerrum and Irving-Rossotti methods.
Abstract: Creatinine is a physiological component of blood, brain and muscles and an important bioligand, which is the last product of the nitrogen metabolism in the vertebrates. In this study , the stability constants of binary complexes formed by creatinine with Cu(II), Co(II), Mn(II), Cr(III), and of the mixedligand complex Cu(II)-creatinine-l-asparagine were determined by the Calvin-Bjerrum and Irving-Rossotti methods. The protonation constant and dissociation constant of creatinine was found to be 4. 90 at 25 C and for 1= 0.1. The conditional formation constants and the formation pH ranges of complexes were determined. Relative abundance was plotted using conditional formation constants of the complexes and the steps of the complexes are shown in graphs. The composition of metal-creatinine complexes was determined as metal/ligand = 1 :1 .
4 citations
TL;DR: Pd(creat)2Cl2·2H2O crystallizes in space group P&1macr; with a= 7.257(2), b= 8.159 (2), c= 14.640(2) A, f = 73.0(1), u = 72.22 (2)°, Z=2, and represents a new allotropic form of this compound as discussed by the authors.
Abstract: Pd(creat)2Cl2·2H2O crystallizes in space group P&1macr; with a= 7.257(2), b= 8.159(2), c= 14.640(2) A, f =73.97(2), g =77.0(1), u =72.22(2)°, Z=2, and represents a new allotropic form of this compound. Pd atoms have planar fourfold coordination of N and Cl atoms in trans configuration. Creatinine moieties are coordinated to the Pd atoms via endocyclic N atoms and their essential planarity causes significant delocalization of electron density. The structure is stabilized by a system of weak hydrogen bonds involving interstitial water molecules and creatinine amino-groups.
4 citations
TL;DR: In this paper, five coordination modes have been established by X-ray crystallography: bidentate bridging through N(l)(r ing) and deprotonated exocyclic NH site 191, Bidentate binding via N ( l ) (ring) and the exocycyclic 0 ( C = 0 ) (11); monodentate binding through the N (l ) ( ring) site /11/; monodente binding through N (c = 0 ǫ ) /12/; and monodenta binding through
Abstract: Creatinine, being a natural metabolite of creatin, is a very important bioligand. Its importance in clinical chemistry is well recognized; its level in serum and urine is indicative of the renal function / l , 2/. The complexation ability of creatinine, due to the presence of several donor groups in its main tautomeric form, is well recognised and studies on the metal ion interactions with creatinine may be helpful in deciphering creatinine metabolic pathways /3, 4, 5, 6, 7/. The study of binary and ternary complexes of this ligand should be of interest due to the fact that creatinine metabolism might be connected with its complcxation to different metal ions 191. Five co-ordination modes have been established by X-ray crystallography:bidentate bridging through N(l)(r ing) and deprotonated exocyclic NH site 191, bidentate binding via N ( l ) (ring) and the exocyclic 0 ( C = 0 ) (11); monodentate binding through the N ( l ) (ring) site /11/; monodentate binding through the exocyclic 0 ( C = 0 ) /12/; and monodentate fashion through the deprotonated exocyclic NH group /10/.
2 citations
TL;DR: In this article, the authors presented a decomposition sequence of creatinine complexes of nickel(II) with various anions and showed that the loss of coordinated water is reversible in the case of [Ni(creat)2(H2O)2]Cl2.
2 citations
TL;DR: Using 195Pt NMR spectroscopy, several products formed in the 1 : 1 reaction at pH = 6-7 of cis-[Pt(NH3)2(H2O)2]2+ with creatinine (C4H7N3O) have been identified at pH 4 in aqueous solution as discussed by the authors.
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Abstract: Phenylmercury(II) replaces a proton of creatine, H2NC+(NH2)NMeCH2C02-, in basic solution to form the zwitterionic
complex PhHgNHC+(NH2)NMeCH2CO2-. Creatine and creatinine (C4H7N30) react with PhHg((OH)N03)I/2 in aqueous ethanol to form a 2:l complex [(PhHg)2(C4H6N30][N03] which exists in two crystalline forms. Creatinine forms a 1:l
complex [PhHg(C4H7N30)][N03].1/2H20 at pH 1.4 on reaction with PhHg((OH)N03)l/2 in the presence of nitric acid.
The 1:l and 2:l complexes may be interconverted. Creatinine hydronitrate, [H2NCNMeCH2CONH][NO3], and the PhHg(II) complexes of creatinine have similar infrared (including deuterated derivatives) and 1H NMR spectra, consistent with retention of the creatinine ring and presence of a guanidinium group in the complexes. An X-ray structural analysis of one crystalline form of the 2:l complex shows bonding of PhHg(II) groups to the exocyclic and ring nitrogens of creatinine to form the cation
[PhHgNHCNMeCH2CONHgPh]+.
23 citations
11 citations