Cross talk between mitochondria and NADPH oxidases
Citations
2,893 citations
Cites background from "Cross talk between mitochondria and..."
...was not found in mitochondria, and furthermore, that the specific activity of Nox in mitochondria is not measurable (111)....
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2,813 citations
Cites background or methods from "Cross talk between mitochondria and..."
...A dysregulation in this relationship may drive the vicious feed-forward cycle of ROS accumulation that can enhance inflammatory response in different diseases (96, 380)....
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...Moreover, Ang II-mediated mitochondrial dysfunction has been shown to increase the expression and activity of NOX1 and NOX4 in vascular smooth muscle cells (96)....
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...In contrast, ROS produced by the mitochondria on serum withdrawal has been shown to trigger NOX1 activation (96)....
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...Recent reports have highlighted an interesting concept of cross-talk between MtROS and NADPH oxidase, which can drive both feed-forward and feedback regulations of NADPH oxidases (73, 96)....
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...Ang II-stimulated mitochondrial H2O2 was blocked by NADPH oxidase inhibitor apocynin and protein kinase C inhibitor chelerythrine (96)....
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References
5,873 citations
"Cross talk between mitochondria and..." refers background in this paper
...Nox3 is expressed in the brain and inner ear [86]....
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...The Nox enzymes contribute to numerous biological and pathological processes, including hearing and balance (Nox3), blood pressure regulation, inflammation, cell growth (Nox1/Nox2), and differentiation (Nox4) [86]....
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4,691 citations
3,812 citations
"Cross talk between mitochondria and..." refers background in this paper
...result of endogenous and mitochondrial ROS play an important role in the degenerative processes [161]....
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2,959 citations
"Cross talk between mitochondria and..." refers background in this paper
...These include the NADPH oxidases [18], xanthine oxidase [19], uncoupled NO synthase [20], and the mitochondrial electron transport chain [16]....
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...This is partly due to low metabolic activity and the lack of information regarding regulation of mitochondrial ROS compared with other enzymes such as NADPH oxidase [18]....
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2,787 citations